Lee, Howard
Department
Clinical Pharmacology and Therapeutics
Specialty
Appointment
First-episode schizophrenia , artificial intelligence in drug development , Personalized medication therapy , Drug therapy in special group , Therapeutic drug concentration monitoring
Education / Career
| Article | A target-mediated drug disposition population pharmacokinetic model of GC1118, a novel anti-EGFR antibody, in patients with solid tumors | ||
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| Announcements | CTS-CLINICAL AND TRANSLATIONAL SCIENCE | Date of publication | 2021-5 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33382918/ | ||
| Article | A phase I study to evaluate the safety, tolerability, pharmacodynamic and pharmacokinetic profiles of ocular GLH8NDE in healthy male adults | ||
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| Announcements | CTS-CLINICAL AND TRANSLATIONAL SCIENCE | Date of publication | 2021-2 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/34523814/ | ||
| Article | An Investigation of the Metabolism and Excretion of KD101 and Its Interindividual Differences: A Microtracing Mass Balance Study in Humans | ||
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| Announcements | CTS-CLINICAL AND TRANSLATIONAL SCIENCE | Date of publication | 2021-1 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33460293/ | ||
| Article | Altered gene expression profiles in peripheral blood mononuclear cells in obese subjects. | ||
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| Announcements | OBESITY FACTS | Date of publication | 2020-7 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32544907/ | ||
| Article | Scientific considerations for global drug development. | ||
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| Announcements | SCIENCE TRANSLATIONAL MEDICINE | Date of publication | 2020-7 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32727913/ | ||
| Article | A critical review of the united states regulatory pathways for determining the equivalence of efficacy between ct-p13 and original infliximab (remicade ?. | ||
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| Announcements | DRUG DESIGN DEVELOPMENT AND THERAPY | Date of publication | 2020-7 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32764882/ | ||
| Article | Phase 1 study of cwp232291 in patients with relapsed or refractory acute myeloid leukemia and myelodysplastic syndrome. | ||
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| Announcements | BLOOD ADVANCES | Date of publication | 2020-5 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32396615/ | ||
| Article | A machine learning-based identification of genes affecting the pharmacokinetics of tacrolimus using the dmet tm plus platform. | ||
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| Announcements | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | Date of publication | 2020-4 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32260456/ | ||
| Article | The road to biosimilars in rare diseases - ongoing lessons from gaucher disease. | ||
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| Announcements | AMERICAN JOURNAL OF HEMATOLOGY | Date of publication | 2020-3 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31816110/ | ||
| Article | The current status of drug repositioning and vaccine developments for the covid-19 pandemic. | ||
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| Announcements | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | Date of publication | 2020-2 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33371468/ | ||
| Article | Safety, tolerability and pharmacokinetics and pharmacodynamics of hl2351, a novel hybrid fc-fused interleukin-1 receptor antagonist, in healthy subjects: a first-in-human study. | ||
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| Announcements | BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | Date of publication | 2020-2 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31658396/ | ||
| Article | Human adme for yh12852 using wavelength scanning cavity ring-down spectroscopy (ws-crds) after a low radioactivity dose. | ||
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| Announcements | BIOANALYSIS | Date of publication | 2020-1 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31928227/ | ||
| Article | Hil-7-hyfc, a long-acting il-7, increased absolute lymphocyte count in healthy subjects. | ||
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| Announcements | CTS-CLINICAL AND TRANSLATIONAL SCIENCE | Date of publication | 2020-1 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32339447/ | ||
| Article | Development of a pharmacokinetic model describing neonatal fc receptor-mediated recycling of hl2351, a novel hybrid fc-fused interleukin-1 receptor antagonist, to optimize dosage regimen. | ||
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| Announcements | CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY | Date of publication | 2020-0 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32945613/ | ||
| Article | URC102, a potent and selective inhibitor of hURAT1, reduced serum uric acid in healthy volunteers. | ||
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| Announcements | Rheumatology. | Date of publication | 201911 |
| Co-researcher | Hyun A Lee, Kyung-Sang Yu, Sang-In Park, Seonghae Yoon, Makoto Onohara, Youngjoo Ahn, Howard Lee | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31056705/ | ||
| Article | Association of metabolic and genetic heterogeneity in head and neck squamous cell carcinoma with prognostic implications: integration of FDG PET and genomic analysis. | ||
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| Announcements | EJNMMI research | Date of publication | 201911 |
| Co-researcher | Jinyeong Choi, Jeong-An Gim, Chiwoo Oh, Seunggyun Ha, Howard Lee, Hongyoon Choi, Hyung-Jun Im | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31754877/ | ||
| Article | A First-in-Human Phase I Study of GC1118, a Novel Anti-Epidermal Growth Factor Receptor Antibody, in Patients with Advanced Solid Tumors. | ||
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| Announcements | The oncologist | Date of publication | 201908 |
| Co-researcher | DO-YOUN OH, KEUN-WOOK LEE, SAE-WON HAN, JIN WON KIM, JUNG-WON SHIN, SEONG-JIN JO, JONGHWA WON, SEOKYUNG HAHN, HOWARD LEE, WOO HO KIM, YUNG-JUE BANG | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31164456/ | ||
| Article | Use of Molecular Imaging in Clinical Drug Development: a Systematic Review. | ||
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| Announcements | Nuclear medicine and molecular imaging | Date of publication | 201906 |
| Co-researcher | Hyeomin Son, Kyungho Jang, Heechan Lee, Sang Eun Kim, Keon Wook kang, Howard lee | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31231441/ | ||
| Article | A physiologically-based pharmacokinetic model adequately predicted the human pharmacokinetic profiles of YH4808, a novel K+-competitive acid blocker. | ||
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| Announcements | European journal of pharmaceutical sciences | Date of publication | 201905 |
| Co-researcher | Lee HA, Lee KR, Jang SB, Chung SY, Yu KS, HL | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/30641142/ | ||
| Article | Development of a Korean-specific virtual population for physiologically based pharmacokinetic modelling and simulation. | ||
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| Announcements | Biopharmaceutics & drug disposition | Date of publication | 201904 |
| Co-researcher | Yun Kim Oliver Hatley Su‐jin Rhee Sojeong Yi Hyun A. Lee Sumin Yoon Jae‐Yong Chung Kyung‐Sang Yu Howard Lee | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/30921829/ | ||
| Article | What Does it Take to Make Model-Informed Precision Dosing Common Practice? Report from the 1st Asian Symposium on Precision Dosing. | ||
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| Announcements | The AAPS journal | Date of publication | 201901 |
| Co-researcher | Polasek TM, Rostami-Hodjegan A, Yim DS, Jamei M, Lee H, Kimko H, Kim JK, Nguyen PTT, Darwich AS, Shin JG | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/30627939/ | ||
| Article | A first-in-human phase i study of gc1118, a novel anti-epidermal growth factor receptor antibody, in patients with advanced solid tumors. | ||
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| Announcements | ONCOLOGIST | Date of publication | 2019-8 |
| Co-researcher | |||
| Article | Development of a korean-specific virtual population for physiologically based pharmacokinetic modelling and simulation. | ||
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| Announcements | BIOPHARMACEUTICS & DRUG DISPOSITION | Date of publication | 2019-4 |
| Co-researcher | |||
| Article | A physiologically-based pharmacokinetic model adequately predicted the human pharmacokinetic profiles of yh4808, a novel k+-competitive acid blocker. | ||
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| Announcements | EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES | Date of publication | 2019-3 |
| Co-researcher | |||
| Article | What does it take to make model-informed precision dosing common practice? report from the 1st asian symposium on precision dosing. | ||
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| Announcements | AAPS JOURNAL | Date of publication | 2019-1 |
| Co-researcher | |||
| Article | Urc102, a potent and selective inhibitor of hurat1, reduced serum uric acid in healthy volunteers. | ||
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| Announcements | RHEUMATOLOGY | Date of publication | 2019-1 |
| Co-researcher | |||
| Article | Association of metabolic and genetic heterogeneity in head and neck squamous cell carcinoma with prognostic implications: integration of fdg pet and genomic analysis. | ||
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| Announcements | EJNMMI RESEARCH | Date of publication | 2019-1 |
| Co-researcher | |||
| Article | Lack of a Clinically Significant Pharmacokinetic Interaction Between Pregabalin and Thioctic Acid in Healthy Volunteers | ||
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| Announcements | Clinical therapeutics | Date of publication | 201810 |
| Co-researcher | Rhee SJ, Lee H, Ahn LY, Lim KS, Yu KS | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/30241687/ | ||
| Article | Data exclusivity through New Drug Reexamination in Korea: sibutramine hydrochloride (Reductil®) vs. sibutramine mesylate (Slimmer®) as an example | ||
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| Announcements | Translational and Clinical Pharmacology | Date of publication | 201806 |
| Co-researcher | HL | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32055548/ | ||
| Article | Failure mode and effects analysis drastically reduced potential risks in clinical trial conduct. | ||
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| Announcements | Drug Des Devel Ther | Date of publication | 201710 |
| Co-researcher | Lee H,Lee H,Baik J,Kim H,Kim R. | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/29089745/ | ||
| Article | New tablet formulation of tacrolimus with smaller interindividual variability may become a better treatment option than the conventional capsule formulation in organ transplant patients. | ||
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| Announcements | Drug Des Devel Ther | Date of publication | 201709 |
| Co-researcher | Kim YK,Kim A,Park SJ,Lee H. | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/29033547/ | ||
| Article | Pharmacokinetics, Safety, and Tolerability of Tedizolid Phosphate After Single-dose Administration in Healthy Korean Male Subjects. | ||
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| Announcements | Clin Ther | Date of publication | 201709 |
| Co-researcher | Kim Y, Kim A, Lee S, Choi SH, Lee DY, Song JS, Lee H, Jang IJ, Yu KS | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/28865799/ | ||
| Article | An accelerator mass spectrometry-enabled microtracer study to evaluate the first-pass effect on the absorption of YH4808. | ||
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| Announcements | Clin Pharmacol Ther | Date of publication | 201709 |
| Co-researcher | Kim A,Yu BY,Dueker SR,Shin KH,Kim HS,Ahn H,Cho JY,Yu KS,Jang IJ,Lee H | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/28214288/ | ||
| Article | A novel K+ competitive acid blocker, YH4808, sustains inhibition of gastricacid secretion with a faster onset than esomeprazole: randomised clinicalstudy in healthy volunteers. | ||
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| Announcements | Alimentary pharmacology & therapeutics. | Date of publication | 201708 |
| Co-researcher | Yi S,Lee H,Jang SB,Byun HM,Yoon SH,Cho JY,Jang IJ,Yu KS | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/28543183/ | ||
| Article | LBEC0101, A Proposed Etanercept Biosimilar: Pharmacokinetics, Immunogenicity, and Tolerability Profiles Compared with a Reference Biologic Product in Healthy Male Subjects. | ||
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| Announcements | BioDrugs | Date of publication | 201708 |
| Co-researcher | Lee H,Chung H,Lee S,Lee H,Yang SM,Yoon SH,Cho JY,Jang IJ,Yu KS. | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/28551775/ | ||
| Article | Pediatric patients undergoing hematopoietic stem cell transplantation can greatly benefit from a novel once-daily intravenous busulfan dosing nomogram. | ||
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| Announcements | Am. J. Hematol. | Date of publication | 201707 |
| Co-researcher | Rhee SJ, Lee JW, Yu KS, Hong KT, Choi JY, Hong CR, Park KD, Shin HY, Song SH, Kang HJ, Lee H | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/28370238/ | ||
| Article | A pharmacogenomic study on the pharmacokinetics of tacrolimus in healthy subjects using the DMETTM Plus platform. | ||
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| Announcements | Pharmacogenomics J | Date of publication | 201705 |
| Co-researcher | Choi Y, Jiang F, An H, Park HJ, Choi JH,Lee H | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/26882121/ | ||
| Article | The novel carboxylesterase 1 variant c.662A>G may decrease the bioactivation of oseltamivir in humans. | ||
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| Announcements | PLoS ONE | Date of publication | 201704 |
| Co-researcher | Oh J, Lee S, Lee H, Cho JY, Yoon SH, Jang IJ, Yu KS, Lim KS | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/28437488/ | ||
| Article | Determination of the starting dose in the first-in-human clinical trials with monoclonal antibodies: a systematic review of papers published between 1990 and 2013. | ||
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| Announcements | Drug Des Devel Ther | Date of publication | 201612 |
| Co-researcher | Suh HY,Peck CC,Yu KS,Lee H | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/27994442/ | ||
| Article | A thorough QT study to evaluate the QTc prolongation potential of two neuropsychiatric drugs, quetiapine and escitalopram, in healthy volunteers | ||
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| Announcements | Int Clin Psychopharmacol | Date of publication | 201607 |
| Co-researcher | Kim A,Lim KS,Lee H,Chung H,Yoon SH,Yu KS,Cho JY,Jang IJ,Chung JY. | ||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/26950553/ | ||
| Article | Pharmacokinetics, pharmacodynamics, and tolerability of LC350189, a novel xanthine oxidase inhibitor, in healthy subjects. | ||
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| Announcements | Drug Des Devel Ther | Date of publication | 2015.08 |
| Co-researcher | Yoon S,Shin D,Lee H,Jang IJ,Yu KS. | ||
| Article | Erratum to: Is Extrapolation of the Safety and Efficacy Data in One Indication to Another Appropriate for Biosimilars? | ||
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| Announcements | AAPS J | Date of publication | 2015.08 |
| Co-researcher | Lee H | ||
| Article | A pharmacokinetic comparison of two voriconazole formulations and the effect of CYP2C19 polymorphism on their pharmacokinetic profiles. | ||
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| Announcements | Drug Des Devel Ther | Date of publication | 2015.05 |
| Co-researcher | Chung H, Lee H, Han H, An H, Lim KS, Lee Y, Cho JY, Yoon SH, Jang IJ, Yu KS. | ||
| Article | Response to "Induction of both P-glycoprotein and specific cytochrome P450 by aspirin eventually does not alter the antithrombotic effect of clopidogrel" | ||
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| Announcements | Clin Pharmacol Ther | Date of publication | 2015.04 |
| Co-researcher | Oh J,Ji SC,Lee H,Yu KS,Jang IJ. | ||
| Article | A fixed-dose combination tablet of gemigliptin and metformin sustained release has comparable pharmacodynamic, pharmacokinetic, and tolerability profiles to separate tablets in healthy subjects. | ||
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| Announcements | Drug Des Devel Ther | Date of publication | 2015.02 |
| Co-researcher | Park SI, Lee H, Oh J, Lim KS, Jang IJ1, Kim JA, Jung JH, Yu KS | ||
| Article | A bioequivalence study of two levofloxacin tablets in healthy male subjects | ||
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| Announcements | TCP | Date of publication | 2014.12 |
| Co-researcher | Inbum Chung, Seonghae Yoon, SoJeong Yi, Bo-Hyung Kim, Sung-Vin Yim, In-Jin Jang and Howard Lee | ||
| Article | Korean, Japanese, and Chinese populations featured similar genes encoding drug-metabolizing enzymes and transporters: a DMET Plus microarray assessment. | ||
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| Announcements | Pharmacogenet Genomics | Date of publication | 2014.1 |
| Co-researcher | Yi S, An H, Lee H, Lee S, Ieiri I, Lee Y, Cho JY, Hirota T, Fukae M, Yoshida K, Nagatsuka S, Kimura M, Irie S, Sugiyama Y, Shin DW, Lim KS, Chung JY, Yu KS, Jang IJ | ||
| Article | Evaluation of the pharmacokinetic and pharmacodynamic drug interactions between cilnidipine and valsartan, in healthy volunteers | ||
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| Announcements | Drug Des Devel Ther | Date of publication | 2014.1 |
| Co-researcher | Lee J, Lee H, Jang K, Lim KS, Shin D, Yu KS. | ||
| Article | Effects of HM30181, a P-glycoprotein inhibitor, on the pharmacokinetics and pharmacodynamics of loperamide in healthy volunteers. | ||
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| Announcements | Br J Clin Pharmacol | Date of publication | 2014.09 |
| Co-researcher | Kim TE, Lee H, Lim KS, Lee S, Yoon SH, Park KM, Han H, Shin SG, Jang IJ, Yu KS, Cho JY | ||
| Article | An assessment of the pharmacokinetics, pharmacodynamics, and tolerability of GCPGC, a novel pegylated granulocyte colony-stimulating factor (G-CSF), in healthy subjects. | ||
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| Announcements | Invest New Drugs | Date of publication | 2014.08 |
| Co-researcher | Shin KH, Lim KS, Lee H, Jang IJ, Yu KS. | ||
| Article | Predictive performance of gentamicin dosing nomograms. | ||
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| Announcements | Drug Des Devel Ther | Date of publication | 2014.08 |
| Co-researcher | Lee J, Yoon S, Shin D, Han H, An H, Lee J, Lim KS, Yu KS, Lee H. | ||
| Article | Effects of proton pump inhibitors on metformin pharmacokinetics and pharmacodynamics. | ||
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| Announcements | Drug Metab Dispos | Date of publication | 2014.07 |
| Co-researcher | Kim A, Chung I, Yoon SH, Yu KS, Lim KS, Cho JY, Lee H, Jang IJ, Chung JY | ||
| Article | Novel nanocrystal formulation of megestrol acetate has improved bioavailability compared with the conventional micronized formulation in the fasting state. | ||
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| Announcements | Drug Des Devel Ther | Date of publication | 2014.06 |
| Co-researcher | Jang K, Yoon S, Kim SE, Cho JY, Yoon SH, Lim KS, Yu KS, Jang IJ, Lee H | ||
| Article | Pharmacokinetic and pharmacodynamic interaction between gemigliptin and metformin in healthy subjects. | ||
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| Announcements | Clin Drug Investig | Date of publication | 2014.06 |
| Co-researcher | Shin D, Cho YM, Lee S, Lim KS, Kim JA, Ahn JY, Cho JY, Lee H, Jang IJ, Yu KS | ||
| Article | Aspirin decreases systemic exposure to clopidogrel through modulation of p-glycoprotein but does not alter its antithrombotic activity. | ||
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| Announcements | Clin Pharmacol Ther | Date of publication | 2014.06 |
| Co-researcher | Oh J, Shin D, Lim KS, Lee S, Jung KH, Chu K, Hong KS, Shin KH, Cho JY, Yoon SH, Ji SC, Yu KS, Lee H, Jang IJ | ||
| Article | Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers. | ||
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| Announcements | Drug Des Devel Ther | Date of publication | 2014.01 |
| Co-researcher | Yoon S, Lee H, Kim TE, Lee S, Chee DH, Cho JY, Yu KS, Jang IJ. | ||
| Article | Pharmacokinetic Properties and Effects of PT302 After Repeated Oral Glucose Loading Tests in a Dose-Escalating Study | ||
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| Announcements | Clin Ther | Date of publication | 2014.01 |
| Co-researcher | Gu N, Cho SH, Kim J, Shin D, Seol E, Lee H, Lim KS, Shin SG, Jang IJ, Yu KS | ||
| Article | Is extrapolation of the safety and efficacy data in one indication to another appropriate for biosimilars? | ||
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| Announcements | AAPS J | Date of publication | 2014.01 |
| Co-researcher | Lee H | ||
| Article | Genetic algorithm guided population pharmacokinetic model development for simvastatin, concurrently or non-concurrently co-administered with amlodipine | ||
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| Announcements | J Clin Pharmacol | Date of publication | 2014.01 |
| Co-researcher | Chaturvedula A, Sale ME, Lee H | ||
| Article | Usefulness of oral loading of oxcarbazepine suspension in selected patients with epilepsy | ||
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| Announcements | International Journal of Clinical Pharmacology and Therapeutics | Date of publication | 2013 |
| Co-researcher | Kim DW, Gu N, Lee H, Jang IJ, Chu K, Yu KS, Cho JY, Yoon SH, Na HJ, Lee SG | ||
| Article | Sustained Increase in the Oral Bioavailability of Loperamide after a Single Oral Dose of HM30181, a P-glycoprotein Inhibitor, in Healthy Male Subjects | ||
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| Announcements | Basic & Clinical Pharmacology & Toxicology | Date of publication | 2013 |
| Co-researcher | Cha YJ, Lee H, Gu N, Kim TE, Lim KS, Yoon SH, Chung JY, Jang IJ, Shin SG, Yu KS, Cho JY. | ||
| Article | Ambulatory blood pressure response to once-daily fimasartan: an 8-week, randomized, double-blind, valsartan-referenced, parallel-group, multicenter study in Korean patients with mild-to-moderate essential hypertension | ||
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| Announcements | Clinical Therapeutics | Date of publication | 2013 |
| Co-researcher | Lee H, KS Kim, SC Chae, MH Jeon, D-S Kim, B-H Oh | ||
| Article | A Population Pharmacokinetic Analysis of Fimasartan, a Selective Angiotensin II Receptor Antagonist, in Healthy Caucasian Subjects and Korean Patients with Hypertension | ||
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| Announcements | Clinical Pharmacology in Drug Development | Date of publication | 2013 |
| Co-researcher | Lee H, IJ Jang, KS Yu, J Choi, BH Oh | ||
| Article | Efficacy and Tolerability of Once-Daily Oral Fimasartan 20 to 240 mg/d in Korean Patients with Hypertension: Findings from Two Phase II, Randomized, Double-Blind, Placebo-Controlled Studies | ||
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| Announcements | Clinical Therapeutics | Date of publication | 2012.04 |
| Co-researcher | Lee H, Yang HM, Lee HY, Kim JJ, Choi DJ, Seung KB, Jeon ES, Ha JW, Rim SJ, Park JB, Shin JH, Oh BH | ||
| Article | Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Fimasartan, a Novel Angiotensin II Receptor Antagonist, Following Single and Repeated Oral Administration in the Fasted and Fed Stated in Healty Subjects | ||
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| Announcements | American Journal of Cardiovascular Drugs | Date of publication | 2011.01 |
| Co-researcher | Chi YH, Lee H, Paik SH, Lee JH, Yoo BW, Kim JH, Tan HK, Kim SL | ||
| Article | Poupulation Pharmacokinetic of Golimumab in Patients with Ankylosing Spondylitis: Impact of Body Weight and Immunogenicity | ||
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| Announcements | International Journal of Clinical Pharmacology and Therapeutics | Date of publication | 2010.09 |
| Co-researcher | Xu ZH, Lee H, Vu T, Hu C, Yan H, Baker D, Hsu B, Pendley C, Wagner C, Davis HM, Zhou H | ||
| Article | Non-concurrent Dosing Attenuated Pharmacokinetic Drug Interaction between Amlodipine and Simvastation | ||
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| Announcements | International Journal of Clinical Pharmacology and Therapeutics | Date of publication | 2010.08 |
| Co-researcher | Park CG, Lee H, Choi JW, Lee SJ, Kim SH, Lim HE | ||
| Article | Clonidine Clearance Matures Rapidly during the Early Postnatal Period: A Population Pharmacokinetic Analysis in Newborns with Neonatal | ||
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| Announcements | Journal of Clinical Pharmacology | Date of publication | 2010.05 |
| Co-researcher | Xie HG, Cao YJ, Gauda EB, Agthe AG, Hendrix CW, Lee H | ||
| Article | Population Pharmacokinetics of Golimumab, and Anti-Tumor Necrosis Factor-α Human Monoclonal Antibody, in Patients with Psoriatic Arthritis. | ||
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| Announcements | Journal of Clinical Pharmacology | Date of publication | 2009.07 |
| Co-researcher | Xu Z, Vu T, Lee H, Hu C, Ling J, Yan H, Baker D, Beutler A, Pendley C, Wagner C, Davis HM, Zhou H | ||
| Article | Suboptimal Aminoglycoside Dosing in Critically ill Patients | ||
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| Announcements | Therapeutic Drug Monitoring | Date of publication | 2008.12 |
| Co-researcher | Rea RS, Capitano B, Bies R, Bigos KL, Smith R, Lee H | ||
| Article | Once-Daily Enoxaparin in Pediatric Thromboembolism: A Dose Finding and Pharmacodynamics Study | ||
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| Announcements | Journal of Thrombosis and Haemostasis | Date of publication | 2007.09 |
| Co-researcher | O'Brien SH, Lee H, Ritchey AK | ||
| Article | Simulation of Correlated Continuous and Categorical Variables using a Single Multivariate Distribution | ||
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| Announcements | Journal of Pharmacokinetics and Pharmacodynamics | Date of publication | 2006.12 |
| Co-researcher | Tannenbaum SJ, Holford NH, Lee H, Peck CC, Mould DR | ||
| Article | Evidence of Effectiveness: How Much Can We Extrapolate From Existing Studies? | ||
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| Announcements | AAPS Journal | Date of publication | 2005.12 |
| Co-researcher | Lee H, Yim DS, Zhou H, Peck CC | ||
| Article | Personal Digital Assistant-Based Drug reference Software as Tools to Improve Rational Prescribing: Benchmark Criteria and Performance | ||
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| Announcements | Clinical Pharmacology and Therapeutics | Date of publication | 2005.07 |
| Co-researcher | Knollmann BC, Smyth BJ, Garnett CE, Salesiotis AN, Gvozdjan DM, Berry NS, Lee H, Min FD | ||
| Article | A Pharmacokinetic/Pharmacodynamic Model for the Mobilization of CD34+Hematopoietic Progenitor Cells by AMD3100 | ||
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| Announcements | Clinical Pharmacology and Therapeutics | Date of publication | 2005.05 |
| Co-researcher | Lack NA, Green B, Dale DC, Calandra GB, Lee H, MacFarland RT, Badel K, Liles WC, Bridger G | ||
| Article | Poupulation Pharmacokinetic Analysis and Simulation of the Time Concentration Profile of Etanercept in Pediatric Patients with Juvenile Rheumatoid Arthritis | ||
|---|---|---|---|
| Announcements | Journal of Clinical Pharmacology | Date of publication | 2005.03 |
| Co-researcher | Yim DS, Zhou H, Buckwalter M, Nestorov I, Peck CC, Lee H | ||
| Article | Population pharmacokinetic and pharmacodynamic modeling of etanercept using logistic regression analysis | ||
|---|---|---|---|
| Announcements | Clinical Pharmacology and Therapeutics | Date of publication | 2003.04 |
| Co-researcher | Lee H, Kimko HC, Rogge M, Wang D, Nestorov I, Peck CC | ||
| Article | Postmarketing Drug Dosage Changes of 499 FDA-Approved New Molecular Entities, 1980-1999 | ||
|---|---|---|---|
| Announcements | Pharmacoepidemiology and Drug Safety | Date of publication | 2002.09 |
| Co-researcher | Cross J, Lee H, Westelinck A, Nelson J, Grudzinskas C, Peck C | ||
| Article | Changes in Clinical Trial Practice and the Working Environment in the Korean Pharmaceutical Industry Since the Implementation of Good Clinical Practics | ||
|---|---|---|---|
| Announcements | Drug Information Journal | Date of publication | 2001.01 |
| Co-researcher | Lee H, Kim C, Shin S | ||
| Article | Bioequivalence Study of Cipol-N(Cyclosporine Microemulsion Preparation) in Healty Adults | ||
|---|---|---|---|
| Announcements | Transplantation Proceedings | Date of publication | 1998 |
| Co-researcher | Park MS, Yu NC, Kim YS, Lee HK, Kim KH | ||