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Yoon, Seo Hyun
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Education / Career

Education / Career
Article Pharmacokinetics of fludarabine and its association with clinical outcomes in paediatric haematopoietic stem cell transplantation patients
Announcements Bone Marrow Transplant. Date of publication 201902
Co-researcher Chung H, Hong KT, Lee JW, Rhee SJ, Kim S, Yoon SH, Yu KS, Kang HJ
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29915216/
Education / Career
Article Pharmacokinetics of Ursodeoxycholic Acid in Elderly Volunteers Compared With Younger Adults in a Korean Population.
Announcements Journal of clinical pharmacology Date of publication 201908
Co-researcher Lee S, Yoon S, Chung H, Ji SC, Yoon SH, Yu KS, Cho JY, Chung JY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30882914/
Education / Career
Article Population Pharmacokinetic Study of Prophylactic Fluconazole in Preterm Infants for Prevention of Invasive Candidiasis
Announcements Antimicrobial agents and chemotherapy Date of publication 201905
Co-researcher Kim YK, Lee J, Oh J, Rhee SJ, Shin SH, Yoon SH, Lee S, Kim HS, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30910892/
Education / Career
Article Safety, tolerability and pharmacokinetics and pharmacodynamics of HL2351, a novel hybrid Fc-fused IL-1 receptor antagonist, in healthy subjects: a first-in-human study.
Announcements Br J Clin Pharmacol Date of publication 201910
Co-researcher Jaeseong Oh , Ki Young Huh, Young‐Gyu Cho, Ji‐Eun Cha, Se‐Jin Kim, Seo Hyun Yoon, Sung Sup Park, Hyunyee Yoon, Jieon Lee, Howard Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31658396/
Education / Career
Article Influence of OATP1B1 and BCRP polymorphisms on the pharmacokinetics and pharmacodynamics of rosuvastatin in elderly and young Korean subjects.
Announcements Scientific reports Date of publication 201912
Co-researcher Yun Kim, Seonghae Yoon, Yewon Choi, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang, Kyung-Sang Yu, Jae-Yong Chung
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31857620/
Education / Career
Article Quantitative prediction of hepatic CYP3A activity using endogenous markers in healthy subjects after administration of CYP3A inhibitors or inducers.
Announcements Drug metabolism and pharmacokinetics Date of publication 201908
Co-researcher Jieon Lee, Seo Hyun Yoon, Sojeong Yi, Andrew HyoungJin Kim, Bora Kim,SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Joo-Youn Cho
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31088714/
Education / Career
Article A non-linear pharmacokinetic-pharmacodynamic relationship of metformin in healthy volunteers: An open-label, parallel group, randomized clinical study.
Announcements PloS one Date of publication 201801
Co-researcher Chung H,Oh J,Yoon SH,Yu KS,Cho JY,Chung JY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29342199/
Education / Career
Article Early Therapeutic Drug Monitoring of Posaconazole Oral Suspension in Patients With Hematologic Malignancies.
Announcements Ther Drug Monit Date of publication 201802
Co-researcher Suh HJ, Kim I, Cho JY, Park SI, Yoon SH, Hwang JH, Bae JY, Lee JO, Koh Y, Song KH, Choe PG, Yu KS, Kim ES, Kim HB, Bang SM, Kim NJ, Song SH, Park WB, Oh MD
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29189664/
Education / Career
Article The Genetic Polymorphism UGT1A4*3 Is Associated with Low Posaconazole Plasma Concentrations in Hematological Malignancy Patients Receiving the Oral Suspension.
Announcements Antimicrob Agents Chemother Date of publication 2018.06
Co-researcher Suh HJ, Yoon SH, Yu KS, Cho JY, Park SI, Lee E, Lee JO, Koh Y, Song KH, Choe PG, Kim ES, Bang SM, Kim HB, Kim I, Kim NJ, Song SH, Park WB, Oh MD
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29661871/
Education / Career
Article A phase 4 study of nilotinib in Korean patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTKorea
Announcements Cancer medicine Date of publication 2018.05
Co-researcher Shin J, Koh Y, Yoon SH, Cho JY, Kim DY, Lee KH, Kim HJ, Ahn JS, Kim YK, Park J, Sohn SK, Moon JH, Lee YJ, Yoon S, Lee JO, Cheong JW, Kim KH, Kim SH, Kim HG, Kim H, Nam SH, Do YR, Park SG, Park SK, Bae SH, Song HH, Shin DY, Oh D, Kim MK, Jung CW, Park S, Kim I
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29577674/
Education / Career
Article Effect of food on the pharmacokinetics of YH4808, a potassium-competitive acid blocker, after single- and multiple-oral dosing in healthy subjects.
Announcements EUR J CLIN PHARMACOL Date of publication 201810
Co-researcher Kim E, Kim A, Yi S, Kim YK, Jang SB, Byun HM, Yoon SH, Cho JY, Jang IJ, Yu KS, Lee S
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29907887/
Education / Career
Article Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity.
Announcements Genomics & informatics. Date of publication 201809
Co-researcher Oh J, Yi S, Gu N, Shin D, Yu KS, Yoon SH, Cho JY, Jang IJ
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30309203/
Education / Career
Article Pharmacokinetics and effect on the corrected QT interval of single-dose escitalopram in healthy elderly compared with younger adults.
Announcements Int Clin Psychopharmacol Date of publication 201701
Co-researcher Chung H,Kim A,Lim KS,Park SI,Yu KS,Yoon SH,Cho JY,Chung JY.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/27741028/
Education / Career
Article Effects of renal impairment on the pharmacokinetics and pharmacodynamics of a novel DPP-IV inhibitor, evogliptin (DA-1229).
Announcements Diabetes Obes Metab Date of publication 201702
Co-researcher Oh J,Kim AH,Lee S,Cho H,Kim YS,Bahng MY,Yoon SH,Cho JY,Jang IJ,Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/27761990/
Education / Career
Article The novel carboxylesterase 1 variant c.662A>G may decrease the bioactivation of oseltamivir in humans.
Announcements PLoS ONE Date of publication 201704
Co-researcher Oh J, Lee S, Lee H, Cho JY, Yoon SH, Jang IJ, Yu KS, Lim KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28437488/
Education / Career
Article A randomized, double-blind, single-dose, two-arm, parallel study comparing pharmacokinetics, immunogenicity and tolerability of branded adalimumab and its biosimilar LBAL in healthy male volunteers.
Announcements Expert Opin Investig Drugs Date of publication 201705
Co-researcher Park KR,Chung H,Yang SM,Lee S,Yoon SH,Cho JY,Jang IJ,Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28290731/
Education / Career
Article Pharmacokinetics and tolerability of DA-8031, a novel selective serotonin reuptake inhibitor for premature ejaculation in healthy male subjects.
Announcements Drug Des Devel Ther Date of publication 201705
Co-researcher Shin D,Lee S,Yi S,Yoon SH,Cho JY,Bahng MY,Jang IJ,Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28331291/
Education / Career
Article Comparison of Plasma Concentrations of Posaconazole with the Oral Suspension and Tablet in Korean Patients with Hematologic Malignancies.
Announcements Infect Chemother Date of publication 201706
Co-researcher Suh HJ,Kim I,Cho JY,Park SI,Yoon SH,Lee JO,Koh Y,Song KH,Choe PG,Yu KS,Kim ES,Kim HB,Bang SM,Kim NJ,Song SH,Park WB,Oh MD
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28608665/
Education / Career
Article Pharmacokinetic comparison using two tablets of an evogliptin/metformin XR 2.5/500 mg fixed dose combination vs. 1 tablet each of evogliptin 5 mg and metformin XR 1,000 mg
.
Announcements Int J Clin Pharmacol Ther Date of publication 201706
Co-researcher Yoon S,Rhee SJ,Park SI,Yoon SH,Cho JY,Jang IJ,Lee S,Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28406090/
Education / Career
Article Distribution of Exogenous and Endogenous CYP3A Markers and Related Factors in Healthy Males and Females.
Announcements AAPS J Date of publication 201707
Co-researcher Lee J,Kim AH,Yi S,Lee S,Yoon SH,Yu KS,Jang IJ,Cho JY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28523515/
Education / Career
Article LBEC0101, A Proposed Etanercept Biosimilar: Pharmacokinetics, Immunogenicity, and Tolerability Profiles Compared with a Reference Biologic Product in Healthy Male Subjects.
Announcements BioDrugs Date of publication 201708
Co-researcher Lee H,Chung H,Lee S,Lee H,Yang SM,Yoon SH,Cho JY,Jang IJ,Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28551775/
Education / Career
Article A novel K+ competitive acid blocker, YH4808, sustains inhibition of gastricacid secretion with a faster onset than esomeprazole: randomised clinicalstudy in healthy volunteers.
Announcements Alimentary pharmacology & therapeutics. Date of publication 201708
Co-researcher Yi S,Lee H,Jang SB,Byun HM,Yoon SH,Cho JY,Jang IJ,Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28543183/
Education / Career
Article Comparable pharmacokinetics and pharmacodynamics of two epoetin alfa formulations Eporon� and Eprex� following a single subcutaneous administration in healthy male volunteers.
Announcements Drug Des Devel Ther Date of publication 201710
Co-researcher Yoon S,Rhee SJ,Heo SJ,Oh TY,Yoon SH,Cho JY,Lee S,Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29138535/
Education / Career
Article Pharmacokinetics and tolerability of MB12066, a beta-lapachone derivative targeting NAD(P)H: quinone oxidoreductase 1: two independent, double-blind, placebo-controlled, combined single and multiple ascending dose first-in-human clinical trials.
Announcements Drug Des Devel Ther Date of publication 201711
Co-researcher Kim S,Lee S,Cho JY,Yoon SH,Jang IJ,Yu KS,
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29158665/
Education / Career
Article Exploration of Biomarkers for Amoxicillin/Clavulanate-Induced Liver Injury: Multi-Omics Approaches.
Announcements CTS-Clinical and Translational Science Date of publication 201705
Co-researcher Lee J,Ji SC,Kim B,Yi S,Shin KH,Cho JY,Lim KS,Lee SH,Yoon SH,Chung JY,Yu KS,Park HS,Kim SH,Jang IJ
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/27785887/
Education / Career
Article Risk factors for suboptimal drug concentration of posaconazole oral suspension in patients with hematologic malignancy.
Announcements JOURNAL DE MYCOLOGIE MEDICALE Date of publication 201712
Co-researcher Kim EJ,Yu KS,Na SH,Nam EY,Oh HS,Kim M,Yoon SH,Lee JO,Koh Y,Song KH,Choe PG,Cho JY,Song SH,Kim ES,Kim HB,Bang SM,Kim NJ,Oh MD,Kim I,Park WB.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28867258/
Education / Career
Article Early Therapeutic Drug Monitoring of Posaconazole Oral Suspension in Patients with Hematologic Malignancies.
Announcements Ther Drug Monit Date of publication 201711
Co-researcher Suh HJ,Kim I,Cho JY,Park SI,Yoon SH,Hwang JH,Bae JY,Lee JO,Koh Y,Song KH,Choe PG,Yu KS,Kim ES,Kim HB,Bang SM,Kim NJ,Oh MD,Song SH,Park WB
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29189664/
Education / Career
Article Inhibition of the MATE transporter by pyrimethamine increases the plasma concentration of metformin but does not increase anti-hyperglycaemic activity in humans.
Announcements Diabetes Obes Metab Date of publication 201601
Co-researcher Oh J,Chung H,Park SI,Yi S,Jang K,Kim A,Yoon J,Cho JY,Yoon SH,Jang IJ,Yu KS,Chung JY.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/26381793/
Education / Career
Article A thorough QT study to evaluate the QTc prolongation potential of two neuropsychiatric drugs, quetiapine and escitalopram, in healthy volunteers.
Announcements Int Clin Psychopharmacol. Date of publication 201607
Co-researcher Kim A, Lim KS, Lee H, Chung H, Yoon SH, Yu KS, Cho JY, Jang IJ, Chung JY.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/26950553/
Education / Career
Article Pharmacokinetics of the evogliptin/metformin extended-release (5/1,000 mg) fixed-dose combination formulation compared to the corresponding loose combination, and food effect in healthy subjects
Announcements Drug Des Devel Ther Date of publication 201604
Co-researcher Su-jin Rhee, SeungHwan Lee, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/27110098/
Education / Career
Article Effectiveness of increasing the frequency of posaconazole syrup administration to achieve optimal plasma concentrations in patients with haematological malignancy.
Announcements Int J Antimicrob Agents Date of publication 201607
Co-researcher Park WB,Cho JY,Park SI,Kim EJ,Yoon S,Yoon SH,Lee JO,Koh Y,Song KH,Choe PG,Yu KS,Kim ES,Bang SM,Kim NJ,Kim I,Oh MD,Kim HB,Song SH.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/27234674/
Education / Career
Article Pharmacokinetic and pharmacodynamic interactions between metformin and a novel dipeptidyl peptidase-4 inhibitor, evogliptin, in healthy subjects.
Announcements Drug Des Devel Ther Date of publication 201608
Co-researcher Rhee SJ,Choi Y,Lee S,Oh J,Kim SJ,Yoon SH,Cho JY,Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/27570447/
Education / Career
Article Pharmacokinetics, Safety, and Tolerability of Metformin in Healthy Elderly Subjects.
Announcements J Clin Pharmacol Date of publication 201609
Co-researcher Jang K,Chung H,Yoon JS,Moon SJ,Yoon SH,Yu KS,Kim K,Chung JY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/26710683/
Education / Career
Article A pharmacokinetic comparison of two voriconazole formulations and the effect of CYP2C19 polymorphism on their pharmacokinetic profiles.
Announcements Drug Des Devel Ther Date of publication 201505
Co-researcher Chung H, Lee H, Han H, An H, Lim KS, Lee Y, Cho JY, Yoon SH, Jang IJ, Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/25999694/
Education / Career
Article Validated LC-MS/MS Assay for the Quantitative Determination of Fimasartan in Human Plasma: Application to Pharmacokinetic Studies.
Announcements J Chromatogr Sci Date of publication 201509
Co-researcher Yoon SH,Oh S,Kim HS,Yi S,Yu KS,Jang IJ,Cho JY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/25616988/
Education / Career
Article Effects of HM30181, a P-glycoprotein inhibitor, on the pharmacokinetics and pharmacodynamics of loperamide in healthy volunteers.
Announcements Br J Clin Pharmacol Date of publication 201409
Co-researcher Kim TE, Lee H, Lim KS, Lee S, Yoon SH, Park KM, Han H, Shin SG, Jang IJ, Yu KS, Cho JY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/24602137/
Education / Career
Article Pharmacodynamics, Pharmacokinetics, and Tolerability of Intravenous or Subcutaneous GC1113, a Novel Erythropoiesis-Stimulating Agent.
Announcements Clin Drug Investig Date of publication 201406
Co-researcher Han H, Lee J, Shin D, Shin KH, Jeon H, Lim KS, Yoon SH, Shin SG, Jang IJ, Cho JY, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/24623104/
Education / Career
Article Aspirin decreases systemic exposure to clopidogrel through modulation of p-glycoprotein but does not alter its antithrombotic activity.
Announcements Clin Pharmacol Ther Date of publication 201406
Co-researcher Oh J, Shin D, Lim KS, Lee S, Jung KH, Chu K, Hong KS, Shin KH, Cho JY, Yoon SH, Ji SC, Yu KS, Lee H, Jang IJ
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/24566733/
Education / Career
Article Effects of proton pump inhibitors on metformin pharmacokinetics and pharmacodynamics.
Announcements Drug Metab Dispos Date of publication 201407
Co-researcher Kim A, Chung I, Yoon SH, Yu KS, Lim KS, Cho JY, Lee H, Jang IJ, Chung JY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/24764147/
Education / Career
Article Tolerability and Pharmacokinetics of Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor-γ Agonist, After a Single Oral Administration in Healthy Female Subjects
Announcements Clin Drug Investig Date of publication 201405
Co-researcher Park MK, Kim TE, Kim J, Kim C, Yoon SH, Cho JY, Jang IJ, Yu KS, Lim KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/24802657/
Education / Career
Article Novel nanocrystal formulation of megestrol acetate has improved bioavailability compared with the conventional micronized formulation in the fasting state.
Announcements Drug Des Devel Ther Date of publication 201406
Co-researcher Jang K, Yoon S, Kim SE, Cho JY, Yoon SH, Lim KS, Yu KS, Jang IJ, Lee H
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/25028536/
Education / Career
Article Pharmacokinetics and tolerability of the new second-generation nonnucleoside reverse- transcriptase inhibitor KM-023 in healthy subjects.
Announcements Drug Des Devel Ther Date of publication 201409
Co-researcher Cha YJ, Lim KS, Park MK, Schneider S, Bray B, Kang MC, Chung JY, Yoon SH, Cho JY, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/25302016/
Education / Career
Article Genetic Polymorphisms of the Carboxylesterase 1 (CES1)Gene in a Korean Population
Announcements TCP Date of publication 201406
Co-researcher Yu-Jung Cha, Hye-Eun Jeong, Jae-Gook Shin, Eun-Young Kim, Kyung-Sang Yu, Joo-Youn Cho, Seo Hyun Yoon, Kyoung Soo Lim
Education / Career
Article Multiple-dose pharmacokinetics and pharmacodynamics of evogliptin (DA-1229), a novel dipeptidyl peptidase IV inhibitor, in healthy volunteers
Announcements Drug Des Devel Ther Date of publication 201410
Co-researcher Gu N, Park MK, Kim TE, Bahng MY, Lim KS, Cho SH, Yoon SH, Cho JY, Jang IJ, Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/25336915/
Education / Career
Article Increased systemic exposure of fimasartan, an angiotensin II receptor antagonist, by ketoconazole and rifampicin
Announcements J Clin Pharmacol Date of publication 201301
Co-researcher Kim JW, Yi S, Kim TE, Lim KS, Yoon SH, Cho JY, Lee MG, Song IS, Shin SG, Jang IJ, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/23400746/
Education / Career
Article Apple juice greatly reduces systemic exposure to atenolol
Announcements Br J Clin Pharmacol Date of publication 201301
Co-researcher Jeon H, Jang IJ, Lee S, Ohashi K, Kotegawa T, Ieiri I, Cho JY, Yoon SH, Shin SG, Yu KS, Lim KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22574741/
Education / Career
Article Global metabolomics and targeted steroid profiling reveal that rifampin, a strong human PXR activator, alters endogenous urinary steroid markers
Announcements J Proteome Res Date of publication 201303
Co-researcher Kim B, Moon JY, Choi MH, Yang HH, Lee S, Lim KS, Yoon SH, Yu KS, Jang IJ, Cho JY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/23320515/
Education / Career
Article Pharmacokinetic-Pharmacodynamic Modelling of Biomarker Response to Sitagliptin in Healthy Volunteers
Announcements Basic Clin Pharmacol Toxicol Date of publication 201308
Co-researcher Kim BH, Kim SE, Kang D, Lim KS, Kim JR, Jang IJ, Shin SG, Yoon SH, Cho JY, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/23510190/
Education / Career
Article Pharmacokinetic and pharmacodynamic properties of a new long-acting granulocyte colony-stimulating factor (HM10460A) in healthy volunteers
Announcements BioDrugs Date of publication 201304
Co-researcher Shin KH, Kim TE, Lim KS, Yoon SH, Cho JY, Kim SE, Park KM, Shin SG, Jang IJ, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/23359067/
Education / Career
Article Population pharmacokinetics of theophylline in premature korean infants
Announcements Ther Drug Monit Date of publication 201306
Co-researcher Kim SE, Kim BH, Lee S, Sohn JA, Kim HS, Cho JY, Yoon SH, Jang IJ, Yu KS, Lim KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/23666573/
Education / Career
Article Sustained Increase in the Oral Bioavailability of Loperamide after a Single Oral Dose of HM30181, a P-glycoprotein Inhibitor, in Healthy Male Subjects.
Announcements Basic & clinical pharmacology & toxicology Date of publication 201307
Co-researcher Cha YJ, Lee H, Gu N, Kim TE, Lim KS, Yoon SH, Chung JY, Jang IJ, Shin SG, Yu KS, Cho JY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/23829508/
Education / Career
Article Usefulness of oral loading of oxcarbazepine suspension in selected patients with epilepsy.
Announcements International journal of clinical pharmacology and therapeutics Date of publication 201310
Co-researcher Kim DW, Gu N, Lee H, Jang IJ, Chu K, Yu KS, Cho JY, Yoon SH, Na HJ, Lee SK
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/23849326/
Education / Career
Article Relationship between absolute neutrophil count profiles and pharmacokinetics of DA-3031, a pegylated granulocyte colony-stimulating factor (pegylated-G-CSF): a dose block-randomized, double-blind, dose-escalation study in healthy subjects.
Announcements Clinical drug investigation Date of publication 201311
Co-researcher Ahn LY, Shin KH, Lim KS, Kim TE, Jeon H, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/24078278/
Education / Career
Article Evaluation of the pharmacokinetic interaction between the dipeptidyl peptidase IV inhibitor LC15-0444 and pioglitazone in healthy volunteers
Announcements INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS Date of publication 201201
Co-researcher Sung Eun Kim, SoJeong Yi, Kwang-Hee Shin, Tae-Eun Kim, Min-Jeong Kim, Youn Hoa Kim, Seo Hyun Yoon, Joo-Youn Cho, Sang-Goo Shin, In-Jin Jang, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22192641/
Education / Career
Article Assessment of the Drug-Drug Interactions between Fimasartan and Hydrochlorothiazide in Healthy Volunteers
Announcements JOURNAL OF CARDIOVASCULAR PHARMACOLOGY Date of publication 201201
Co-researcher Jeon, Hyewon BS; Lim, Kyoung Soo MD, PhD; Shin, Kwang-Hee MS; Kim, Jae Woo MD, MS; Yoon, Seo Hyun PhD; Cho, Joo-Youn PhD; Shin, Sang-Goo MD, PhD; Jang, In-Jin MD, PhD; Yu, Kyung-Sang MD, PhD
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/21934629/
Education / Career
Article Efficacy, tolerability, and pharmacokinetics of oxcarbazepine oral loading in patients with epilepsy.
Announcements Epilepsia Date of publication 201201
Co-researcher Kim DW, Gu N, Jang IJ, Chu K, Yu KS, Cho JY, Yoon SH, Kim HS, Oh J, Lee SK.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22091603/
Education / Career
Article Effect of CYP2C19 Polymorphism on the Pharmacokinetics of Voriconazole After Single and Multiple Doses in Healthy Volunteers.
Announcements J Clin Pharmacol Date of publication 201202
Co-researcher Lee S, Kim BH, Nam WS, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/21383338/
Education / Career
Article Tolerability and pharmacokinetics of a new P-glycoprotein inhibitor, HM30181, in healthy Korean male volunteers: single- and multiple-dose randomized, placebo-controlled studies.
Announcements Clin Ther Date of publication 201202
Co-researcher Kim TE, Gu N, Yoon SH, Cho JY, Park KM, Shin SG, Jang IJ, Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22284902/
Education / Career
Article A positron emission tomography microdosing study with sertraline in healthy volunteers.
Announcements Int J Clin Pharmacol Ther Date of publication 201205
Co-researcher Shin KH, Kim KP, Lim KS, Kim JW, Lee YS, Yang BY, Lee JS, Jung JM, Yoon SH, Jang IJ, Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22373835/
Education / Career
Article Pharmacokinetics and pharmacodynamics of oral tolvaptan administered in 15- to 60-mg single doses to healthy Korean men.
Announcements J Cardiovasc Pharmacol Date of publication 201204
Co-researcher Yi S, Jeon H, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22130104/
Education / Career
Article Assessment of pharmacokinetic proportionality of levofloxacin and cyclosporine over a 100-fold dose range in healthy human volunteers.
Announcements Expert Opin Drug Metab Toxico Date of publication 201204
Co-researcher Lim MS, Seong SJ, Park J, Seo JJ, Lee J, Yu KS, Lee HW, Yoon YR.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22404324/
Education / Career
Article Comparative pharmacokinetics of HD203, a biosimilar of etanercept, with marketed etanercept (Enbrel®): a double-blind, single-dose, crossover study in healthy volunteers.
Announcements BioDrugs Date of publication 201206
Co-researcher Yi S, Kim SE, Park MK, Yoon SH, Cho JY, Lim KS, Shin SG, Jang IJ, Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22515513/
Education / Career
Article Quantitative and Qualitative Analysis of CKD-501, Lobeglitazone, in Human Plasma and Urine Using LC–MS/MS and Its Application to a Pharmacokinetic Study
Announcements Chromatographia Date of publication 201206
Co-researcher Bora Kim, Hyun-Suk Shin, Jung-Ryul Kim, Kyung-Soo Lim, Seo Hyun Yoon, Kyung-Sang Yu, Sang-Goo Shin, In-Jin Jang, Joo-Youn Cho
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/PMID: X/
Education / Career
Article The effect of fimasartan, an Angiotensin receptor type 1 blocker, on the pharmacokinetics and pharmacodynamics of warfarin in healthy korean male volunteers: a one-sequence, two-period crossover clinical trial.
Announcements Clin Ther Date of publication 201207
Co-researcher Gu N, Kim BH, Lim KS, Kim SE, Nam WS, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22727611/
Education / Career
Article Assessment of the pharmacokinetics of co-administered metformin and lobeglitazone, a thiazolidinedione antihyperglycemic agent, in healthy subjects.
Announcements Curr Med Res Opin Date of publication 201207
Co-researcher Shin D, Kim TE, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22697273/
Education / Career
Article Evaluation of the pharmacokinetics, food effect, pharmacodynamics, and tolerability of DA-1229, a dipeptidyl peptidase IV inhibitor, in healthy volunteers: first-in-human study.
Announcements Clin Ther Date of publication 201209
Co-researcher TE Kim, KS Lim, MK Park, SH Yoon, JY Cho, SG Shin, IJ Jang, KS Yu.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22943970/
Education / Career
Article The Effect of Therapeutic Drug Monitoring on Safety and Efficacy of Voriconazole in Invasive Fungal Infections: A Randomized Controlled Trial.
Announcements Clin Infect Dis Date of publication 201210
Co-researcher Park WB, Kim NH, Kim KH, Lee SH, Nam WS, Yoon SH, Song KH, Choe PG, Kim NJ, Jang IJ, Oh MD, Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22761409/
Education / Career
Article Intravenous amantadine for freezing of gait resistant to dopaminergic therapy: a randomized, double-blind, placebo-controlled, cross-over clinical trial.
Announcements PLoS One Date of publication 201211
Co-researcher Kim YE, Yun JY, Yang HJ, Kim HJ, Gu N, Yoon SH, Cho JY, Jeon BS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/23185280/
Education / Career
Article Comparative Pharmacokinetics/Pharmacodynamics of Clopidogrel Besylate and Clopidogrel Bisulfate in Healthy Korean Subjects
Announcements Clin Drug Investig Date of publication 201212
Co-researcher Kim, Bo-Hyung; Kim, Jung-Ryul; Lim, Kyoung Soo; Shin, Hyun-Suk; Yoon, Seo Hyun; Cho, Joo-Youn; Jang, In-Jin; Shin, Sang-Goo; Yu, Kyung-Sang
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/23026843/
Education / Career
Article Simultaneous LC-MS-MS Determination of HM30181A, [2-(2-{4-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethyl]-phenyl}-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl]amide, as a new P-Glycoprotein Inhibitor and Its Two Metabolites, M1 and M2, in Human Plasma: Application to a Pharmacokinetic Study
Announcements CHROMATOGRAPHIA Date of publication 201102
Co-researcher Choi, YH/ Oh, S/ Yoon, SH/ Kim, TE/ Gu, N/ Kim, EY/ Kim, HK/ Yu, KS/ Jang, IJ/ Shin, SG )/ Cho, JY
Education / Career
Article Quantification of Ticlopidine in Human Plasma Using Protein Precipitation and Liquid Chromatography Coupled with Tandem Mass
Announcements JOURNAL OF BIOANALYSIS AND BIOMEDICINE Date of publication 201103
Co-researcher Yi SJ, Shin HS, Yoon SH, Yu KS, Jang IJ, Shin SG, Cho JY
Education / Career
Article Effect of multiple doses of fimasartan, an angiotensin II receptor antagonist, on the steady-state pharmacokinetics of digoxin in healthy volunteers
Announcements INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS Date of publication 201105
Co-researcher Yi S, Kim JW, Kim TE, Kim J, Jun YK, Choi J, Yoon SH, Cho JY, Song SH, Shin SG, Jang IJ, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/21543035/
Education / Career
Article Pharmacokinetics of extended-release versus conventional tramadol/acetaminophen fixed-dose combination tablets: an open-label, 2-treatment, multiple-dose, randomized-sequence crossover study in healthy korean male volunteers
Announcements CLINICAL THERAPEUTICS Date of publication 201106
Co-researcher SoJeong Yi, Yong-ju Chun, Tae-Eun Kim, Hyun-Suk Shin , Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang, Sang-Goo Shin, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/21704237/
Education / Career
Article Pharmacokinetic interaction of fimasartan, a new angiotensin II receptor antagonist, with amlodipine in healthy volunteers
Announcements JOURNAL OF CARDIOVASCULAR PHARMACOLOGY Date of publication 201106
Co-researcher SoJeong Yi, Tae-Eun Kim, Seo Hyun Yoon, Joo-Youn Cho, Sang-Goo Shin, In-Jin Jang, and Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/21394036/
Education / Career
Article Immunogenicity and safety of a single intramuscular dose of a diphtheria-tetanus toxoid (Td) vaccine (GC1107) in Korean adults
Announcements VACCINE Date of publication 201110
Co-researcher SeungHwan Lee, Wan Beom Park, Kwang-Hee Shin, Dong Ho Ahn, Seo Hyun Yoon, Joo-Youn Cho, Sang-Goo Shin, In-Jin Jang, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/21864613/
Education / Career
Article Prolonged use of aspirin alters human and rat intestinal cells and thereby limits the absorption of clopidogrel
Announcements CLINICAL PHARMACOLOGY & THERAPEUTICS Date of publication 201110
Co-researcher Jung KH, Chu K, Lee ST, Yoon HJ, Chang JY, Nam WS, Yoon SH, Cho JY, Yu KS, Jang IJ, Kim M, Lee SK, Roh JK
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/21900887/
Education / Career
Article Pharmacokinetics and tolerability of probucol after multiple oral administrations in healthy volunteers
Announcements INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS Date of publication 201111
Co-researcher Jeon H, Lee S, Kim TE, Yoon SH, Shin SG, Jang IJ, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22011694/
Education / Career
Article Open label, three period, single sequence, study of 5, 25, 50 mg sertraline pharmacokinetics in healthy male Korean volunteers
Announcements INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS Date of publication 201111
Co-researcher Park MK, Shin KH, Kim KP, Kim TE, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22011692/
Education / Career
Article Tolerability and Pharmacokinetics of Lobeglitazone (CKD-501), a Peroxisome Proliferator-Activated Receptor-γ Agonist: A Single- and Multiple-Dose, Double-Blind, Randomized Control Study in Healthy Male Korean Subjects
Announcements CLINICAL THERAPEUTICS Date of publication 201111
Co-researcher Jung Won Kim BS, Jung-Ryul Kim MD, PhD, SoJeong Yi MS, Kwang-Hee Shin MS, Hyun-Suk Shin MS, Seo Hyun Yoon PhD, Joo-Youn Cho PhD, Dal-Hyun Kim PhD, Sang-Goo Shin MD, PhD, In-Jin Jang MD, PhD, Kyung-Sang Yu MD, PhD
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22047812/
Education / Career
Article The Effect of the Newly Developed Angiotensin Receptor II Antagonist Fimasartan on the Pharmacokinetics of Atorvastatin in Relation to OATP1B1 in Healthy Male Volunteers
Announcements JOURNAL OF CARDIOVASCULAR PHARMACOLOGY Date of publication 201111
Co-researcher Shin, Kwang-Hee, Kim, Tae-Eun, Kim, Sung Eun, Lee, Min Goo, Song, Im-Sook, Yoon, Seo Hyun, Cho, Joo-Youn, Jang, In-Jin, Shin, Sang-Goo, Yu, Kyung-Sang
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/21765368/
Education / Career
Article Pharmacokinetic Comparison of a New Sustained-Release Formulation of Glimepiride/Metformin 1/500 mg Combination Tablet and a Sustained-Release Formulation of Glimepiride/Metformin 2/500 mg Combination Tablet in Healthy Korean Male Volunteers: A Randomized, 2-Sequence, 2-Period, 2-Treatment Crossover Study
Announcements CLINICAL THERAPEUTICS Date of publication 201111
Co-researcher Kwang-Hee Shin MS, Sung Eun Kim BS, Seo Hyun Yoon PhD, Joo-Youn Cho PhD, In-Jin Jang MD, PhD, Sang-Goo Shin MD, PhD, Kyung-Sang Yu MD, PhD
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/22036245/
Education / Career
Article Influence of Ginkgo biloba extract on the pharmacodynamic effects and pharmacokinetic properties of ticlopidine: an open-label, randomized, two-period, two-treatment, two-sequence, single-dose crossover study in healthy Korean male volunteers
Announcements CLINICAL THERAPEUTICS Date of publication 201002
Co-researcher Kim BH, Kim KP, Lim KS, Kim JR, Yoon SH, Cho JY, Lee YO, Lee KH, Jang IJ, Shin SG, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/20206795/
Education / Career
Article Comparison of the bioavailability and tolerability of fixed-dose combination glimepiride/metformin 2/500-mg tablets versus separate tablets: A single-dose, randomized-sequence, open-label, two-period crossover study in healthy Korean volunteers
Announcements CLINICAL THERAPEUTICS Date of publication 201007
Co-researcher Gu N, Kim BH, Rhim H, Chung JY, Kim JR, Shin HS, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/20678687/
Education / Career
Article Relative Bioavailability and Tolerability of Two Formulations of Bicalutamide 50-mg Tablets: A Randomized-Sequence, Open-Label, Two-Period Crossover Study in Healthy Korean Male Subjects
Announcements CLINICAL THERAPEUTICS Date of publication 201012
Co-researcher Lee S, Yoon SH, Cho JY, Shin SG, Jang IJ, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/21353117/

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