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Cho, Joo-Youn
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Department

Clinical Pharmacology and Therapeutics

Specialty

Pharmacometabolomics , Pharmacogenomics , Clinical drug development

Appointment
Research Profiles

Education / Career

Education / Career
Article Population pharmacokinetic and pharmacodynamic model of evogliptin: Severe uremia increases the bioavailability of evogliptin
Announcements CPT Pharmacometrics Syst Pharmacol Date of publication 202502
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/39465597/
Education / Career
Article Influence of gut bile acid composition on the glucose-lowering effect and safety of metformin
Announcements Br J Clin Pharmacol Date of publication 202412
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/39622250/
Education / Career
Article Comprehensive Evaluation of OATP- and BCRP-Mediated Drug-Drug Interactions of Methotrexate Using Physiologically-Based Pharmacokinetic Modeling
Announcements Clin Pharmacol Ther Date of publication 202410
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38860384/
Education / Career
Article Effect of Narrowband Ultraviolet B Phototherapy on Systemic Metabolome in Korean Patients With Psoriasis
Announcements Exp Dermatol Date of publication 202410
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/39373240/
Education / Career
Article Metabolic profiling of psoriasis vulgaris and palmoplantar pustulosis
Announcements Exp Dermatol Date of publication 202408
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/39166459/
Education / Career
Article Nasal symbiont Staphylococcus epidermidis restricts influenza A virus replication via the creation of a polyamine-deficient cellular environment
Announcements Commun Biol Date of publication 202408
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/39174732/
Education / Career
Article Inhibition of BCAT1-mediated cytosolic leucine metabolism regulates Th17 responses via the mTORC1-HIF1α pathway
Announcements Exp Mol Med Date of publication 202408
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/39085353/
Education / Career
Article Pharmacokinetic Interactions Between the Fixed-Dose Combination of Ezetimibe/Rosuvastatin 10/20 Mg and the Fixed-Dose Combination of Telmisartan/Amlodipine 80/5 Mg in Healthy Subjects
Announcements Drug Des Devel Ther Date of publication 202407
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38974125/
Education / Career
Article Pharmacokinetic interactions between fexuprazan, a potassium-competitive acid blocker, and nonsteroidal anti-inflammatory drugs in healthy males
Announcements Clin Transl Sci Date of publication 202405
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38700290/
Education / Career
Article Pioglitazone-induced alterations of purine metabolism in healthy male subjects
Announcements Clin Transl Sci Date of publication 202405
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38771175/
Education / Career
Article Targeted Metabolomic Biomarkers for Stroke Subtyping
Announcements Transl Stroke Res Date of publication 202404
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36764997/
Education / Career
Article Effects of meal type on the bioavailability of vutiglabridin, a novel anti-obesity agent, in healthy subjects
Announcements Clin Transl Sci Date of publication 202403
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38436494/
Education / Career
Article Pharmacogenetic Analysis of an 8-Year Old Girl with Reye Syndrome Associated with Use of Naproxen
Announcements Am J Case Rep Date of publication 202402
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38311849/
Education / Career
Article Metabolomic Characteristics of Nontuberculous Mycobacterial Pulmonary Disease
Announcements J Infect Dis Date of publication 202402
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38407452/
Education / Career
Article Differences in Brain Metabolite Profiles Between Normothermia and Hypothermia
Announcements J Korean Med Sci Date of publication 202402
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38412613/
Education / Career
Article A 6-month exercise intervention clinical trial in women: effects of physical activity on multi-omics biomarkers and health during the first wave of COVID-19 in Korea
Announcements BMC Sports Sci Med Rehabil Date of publication 202401
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38287431/
Education / Career
Article Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma
Announcements Nat Commun Date of publication 202310
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/37828054/
Education / Career
Article Quantification of OATP1B1 endogenous metabolites coproporphyrin I and III in human urine
Announcements Transl Clin Pharmacol Date of publication 202309
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/37810628/
Education / Career
Article Comparison of the Pharmacokinetics, Safety, and Tolerability of Two Empagliflozin Formulations in Healthy Korean Subjects
Announcements Drug Des Devel Ther Date of publication 202307
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/37521035/
Education / Career
Article Effect of haemodialysis on the pharmacokinetics and pharmacodynamics of evogliptin
Announcements Diabetes Obes Metab Date of publication 202306
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36852751/
Education / Career
Article Serum, Urine, and Fecal Metabolome Alterations in the Gut Microbiota in Response to Lifestyle Interventions in Pediatric Obesity: A Non-Randomized Clinical Trial
Announcements Nutrients Date of publication 202305
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/37432339/
Education / Career
Article Pharmacokinetics of dexmedetomidine in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass
Announcements Paediatr Anaesth Date of publication 202304
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36594749/
Education / Career
Article Baseline Tyrosine Level Is Associated with Dynamic Changes in FAST Score in NAFLD Patients under Lifestyle Modification
Announcements Metabolites Date of publication 202303
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36984884/
Education / Career
Article Protective role of colitis in inflammatory arthritis via propionate-producing Bacteroides in the gut
Announcements Front Immunol Date of publication 202301
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36793721/
Education / Career
Article Identification of Serum Metabolites for Predicting Chronic Kidney Disease Progression according to Chronic Kidney Disease Cause
Announcements Metabolites Date of publication 202211
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36422264/
Education / Career
Article Identification of Metabolic Signature Associated with Idiopathic Inflammatory Myopathy Reveals Polyamine Pathway Alteration in Muscle Tissue
Announcements Metabolites Date of publication 202210
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36295908/
Education / Career
Article Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D
Announcements Nat Commun Date of publication 202210
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36241614/
Education / Career
Article Association of Metabolic Signatures with Nonalcoholic Fatty Liver Disease in Pediatric Population
Announcements Metabolites Date of publication 202209
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36144285/
Education / Career
Article The pharmacokinetic, safety, and tolerability profiles of eslicarbazepine acetate are comparable between Korean and White subjects
Announcements Clin Transl Sci Date of publication 202209
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35727711/
Education / Career
Article Key Considerations for Phase 2 or 3 Clinical Study Design of Anti-Inflammatory Agent for COVID-19 Treatment
Announcements Frontiers in pharmacology. Date of publication 202206
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35721224/
Education / Career
Article An Improved Method to Quantify Short-Chain Fatty Acids in Biological Samples Using Gas Chromatography-Mass Spectrometry
Announcements Metabolites Date of publication 202206
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35736458/
Education / Career
Article Evaluation of food effects on the pharmacokinetics of Pelargonium sidoides and Coptis with each bioactive compound berberine and epicatechin after a single oral dose of an expectorant and antitussive agent UI026 in healthy subjects
Announcements Transl Clin Pharmacol Date of publication 202203
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35419311/
Education / Career
Article Pharmacokinetic and Pharmacodynamic Characteristics of Tripegfilgrastim, a Pegylated G-CSF, in Pediatric Patients with Solid Tumors
Announcements Clin Pharmacol Ther Date of publication 202201
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34605552/
Education / Career
Article A validated simple LC-MS/MS method for quantifying trimethylamine N-oxide (TMAO) using a surrogate matrix and its clinical application
Announcements Translational and clinical pharmacology. Date of publication 202112
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35024362/
Education / Career
Article Endogenous metabolic markers for predicting the activity of dihydropyrimidine dehydrogenase
Announcements Clin Transl Sci Date of publication 202112
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34863048/
Education / Career
Article Metabolomic Signatures for the Effects of Weight Loss Interventions on Severe Obesity in Children and Adolescents
Announcements Metabolites Date of publication 202112
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35050149/
Education / Career
Article Exploration for the effect of renal function and renal replacement therapy on pharmacokinetics of remdesivir and GS-441524 in patients with COVID-19: A limited case series
Announcements Clin Transl Sci Date of publication 202111
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34761554/
Education / Career
Article Comparative pharmacokinetics of Theracurmin, a highly bioavailable curcumin, in healthy adult subjects
Announcements Int J Clin Pharmacol Ther Date of publication 202110
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34423771/
Education / Career
Article Effects of vancomycin-induced gut microbiome alteration on the pharmacodynamics of metformin in healthy male subjects
Announcements Clin Transl Sci Date of publication 202109
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33982376/
Education / Career
Article Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform
Announcements Transl Clin Pharmacol Date of publication 202109
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34621706/
Education / Career
Article Effect of CYP3A4 metabolism on sex differences in the pharmacokinetics and pharmacodynamics of zolpidem
Announcements Sci Rep Date of publication 202109
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34580385/
Education / Career
Article Urine 5-Eicosatetraenoic Acids as Diagnostic Markers for Obstructive Sleep Apnea
Announcements Antioxidants (Basel) Date of publication 202108
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34439490/
Education / Career
Article Changes in the gut microbiome influence the hypoglycemic effect of metformin through the altered metabolism of branched-chain and nonessential amino acids
Announcements Diabetes Res Clin Pract Date of publication 202108
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34329692/
Education / Career
Article Pharmacokinetics, Tolerability and Pharmacogenetics of DA-8031 After Multiple Ascending Doses in Healthy Male Subjects
Announcements Drug Design, Development and Therapy Date of publication 202106
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34103898/
Education / Career
Article Metabolic fingerprinting uncovers the distinction between the phenotypes of tuberculosis-associated COPD and smoking-induced COPD
Announcements Frontiers in Medicine Date of publication 202105
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34055821/
Education / Career
Article Assessment of Oral Vancomycin-Induced Alterations in Gut Bacterial Microbiota and Metabolome of Healthy Men
Announcements Front Cell Infect Microbiol Date of publication 202105
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34123865/
Education / Career
Article Comparison of Pharmacokinetic, Pharmacodynamic and Tolerability Profiles of CKD-11101, Darbepoetin Alfa (NESP�) Biosimilar, to Those of NESP� After a Single Subcutaneous or Intravenous Administration to Healthy Subjects
Announcements Drug Des Devel Ther. Date of publication 202104
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33953543/
Education / Career
Article A pilot study to investigate the utility of NAT2 genotype-guided isoniazid monotherapy regimens in NAT2 slow acetylators
Announcements Pharmacogenetics and genomics. Date of publication 202104
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33165168/
Education / Career
Article Pharmacokinetics and Safety of Extended-release Ranolazine in Korean and White Healthy Subjects
Announcements Clinical therapeutics. Date of publication 202103
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33518355/
Education / Career
Article Metastasis-on-a-chip reveals adipocyte-derived lipids trigger cancer cell migration via HIF-1α activation in cancer cells
Announcements Biomaterials. Date of publication 202102
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33385686/
Education / Career
Article The potential pathways underlying the association of propyl-paraben exposure with aeroallergen sensitization and EASI score using metabolomics analysis
Announcements Sci Rep Date of publication 202102
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33580129/
Education / Career
Article The utility of CYP3A activity endogenous markers for evaluating drug-drug interaction between sildenafil and CYP3A inhibitors in healthy subjects
Announcements Drug Metab Pharmacokinet Date of publication 202102
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33348240/
Education / Career
Article Urinary metabolic markers reflect on hepatic, not intestinal, CYP3A activity in healthy subjects
Announcements Drug Metab Pharmacokinet Date of publication 202102
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33348239/
Education / Career
Article Pharmacokinetics and Pharmacodynamics of Ursodeoxycholic Acid in an Overweight Population With Abnormal Liver Function
Announcements Clinical pharmacology in drug development Date of publication 202101
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32191400/
Education / Career
Article Gut microorganisms and their metabolites modulate the severity of acute colitis in a tryptophan metabolism-dependent manner.
Announcements European journal of nutrition Date of publication 202012
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32055962/
Education / Career
Article Population Pharmacokinetic Analysis of Amikacin for Optimal Pharmacotherapy in Korean Patients with Nontuberculous Mycobacterial Pulmonary Disease
Announcements Antibiotics. Date of publication 202011
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33172135/
Education / Career
Article Impact of vancomycin-induced changes in the intestinal microbiota on the pharmacokinetics of simvastatin.
Announcements Clin Transl Sci Date of publication 202007
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32058642/
Education / Career
Article Development and validation of a method for the simultaneous quantification of endogenous steroids metabolized by CYP3A
Announcements Transl Clin Pharmacol Date of publication 202006
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32656158/
Education / Career
Article Mechanism of Chronic Kidney Disease Progression and Novel Biomarkers: A Metabolomic Analysis of Experimental Glomerulonephritis
Announcements Metabolites Date of publication 202004
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32344531/
Education / Career
Article Phase I and pharmacokinetic study of the vascular-disrupting agent CKD-516 (NOV120401) in patients with refractory solid tumors.
Announcements Pharmacology Research & Perspectives Date of publication 202004
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32162844/
Education / Career
Article A Comprehensive Proteomic and Phosphoproteomic Analysis of Retinal Pigment Epithelium Reveals Multiple Pathway Alterations in Response to the Inflammatory Stimuli
Announcements International journal of molecular sciences Date of publication 202004
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32344885/
Education / Career
Article Pharmacokinetics and Pharmacodynamics of a Fixed-Dose Combination of gemigliptin/metformin Sustained Release 25/500 Mg Compared to the Loose Combination in Healthy Male Subjects
Announcements Translational and clinical pharmacology Date of publication 202003
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32274380/
Education / Career
Article Complex influences of gut microbiome metabolism on various drug responses
Announcements Transl Clin Pharmacol Date of publication 202003
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32274377/
Education / Career
Article External Validation of a Pharmacokinetic Model of Propofol for Target-Controlled Infusion in Children under Two Years Old
Announcements J Korean Med Sci Date of publication 202003
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32193901/
Education / Career
Article Nicotinamide attenuates the decrease in dendritic spine density in hippocampal primary neurons from 5xFAD mice, an Alzheimer's disease animal model.
Announcements Molecular brain. Date of publication 202002
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32033569/
Education / Career
Article Colorectal cancer diagnostic model utilizing metagenomic and metabolomic data of stool microbial extracellular vesicles.
Announcements Scientific reports Date of publication 202002
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32071370/
Education / Career
Article Influence of OATP1B1 and BCRP polymorphisms on the pharmacokinetics and pharmacodynamics of rosuvastatin in elderly and young Korean subjects.
Announcements Scientific reports Date of publication 201912
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31857620/
Education / Career
Article Indoxyl sulfate-induced TNF-α is regulated by crosstalk between the aryl hydrocarbon receptor, NF-κB, and SOCS2 in human macrophages.
Announcements FASEB journal Date of publication 201910
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31284759/
Education / Career
Article A Population Pharmacokinetic Model of Intravenous Dexmedetomidine for Mechanically Ventilated Children after Neurosurgery.
Announcements Journal of clinical medicine. Date of publication 201910
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31581476/
Education / Career
Article Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from Cirrhosis
Announcements Cancers Date of publication 201910
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31590436/
Education / Career
Article Pharmacokinetics of Ursodeoxycholic Acid in Elderly Volunteers Compared With Younger Adults in a Korean Population.
Announcements Journal of clinical pharmacology Date of publication 201908
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30882914/
Education / Career
Article Quantitative prediction of hepatic CYP3A activity using endogenous markers in healthy subjects after administration of CYP3A inhibitors or inducers.
Announcements Drug metabolism and pharmacokinetics Date of publication 201908
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31088714/
Education / Career
Article Comparison of the Plasma Metabolome Profiles Between the Internal Thoracic Artery and Ascending Aorta in Patients Undergoing Coronary Artery Bypass Graft Surgery Using Gas Chromatography Time-of-Flight Mass Spectrometry.
Announcements Journal of Korean medical science (JKMS) Date of publication 201904
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30950250/
Education / Career
Article Ursodeoxycholic acid exerts hepatoprotective effects by regulating amino acid, flavonoid, and fatty acid metabolic pathways
Announcements Metabolomics Society Date of publication 201902
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30830474/
Education / Career
Article A pharmacokinetic drug-drug interaction study between pregabalin and tramadol in healthy volunteers
Announcements EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY Date of publication 201812
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30136102/
Education / Career
Article Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity.
Announcements Genomics & Informatics Date of publication 201811
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30309203/
Education / Career
Article Phloroglucinol ameliorates cognitive impairments by reducing the amyloid beta peptide burden and pro-inflammatory cytokines in the hippocampus of 5XFAD mice
Announcements FREE RADICAL BIOLOGY AND MEDICINE Date of publication 201810
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30118828/
Education / Career
Article Effect of food on the pharmacokinetics of YH4808, a potassium-competitive acid blocker, after single- and multiple-oral dosing in healthy subjects
Announcements EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY Date of publication 201810
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29907887/
Education / Career
Article Regulation of endogenic metabolites by rosuvastatin in hyperlipidemia patients: An integration of metabolomics and lipidomics
Announcements CHEMISTRY AND PHYSICS OF LIPIDS Date of publication 201808
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29852124/
Education / Career
Article The Genetic Polymorphism UGT1A4*3 Is Associated with Low Posaconazole Plasma Concentrations in Hematological Malignancy Patients Receiving the Oral Suspension
Announcements ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Date of publication 201807
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29661871/
Education / Career
Article Assessment of induced CYP3A activity in pregnant women using 4 beta-hydroxycholesterol: Cholesterol ratio as an appropriate metabolic marker
Announcements DRUG METABOLISM AND PHARMACOKINETICS Date of publication 201806
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29759884/
Education / Career
Article A phase 4 study of nilotinib in Korean patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTKorea
Announcements CANCER MEDICINE Date of publication 201805
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29577674/
Education / Career
Article Identification of - or (-1)-Hydroxylated Medium-Chain Acylcarnitines as Novel Urinary Biomarkers for CYP3A Activity
Announcements CLINICAL PHARMACOLOGY & THERAPEUTICS Date of publication 201805
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28877336/
Education / Career
Article Early Therapeutic Drug Monitoring of Posaconazole Oral Suspension in Patients With Hematologic Malignancies
Announcements THERAPEUTIC DRUG MONITORING Date of publication 201802
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29189664/
Education / Career
Article Evaluation of the effects of food on levodropropizine controlled-release tablet and its pharmacokinetic profile in comparison to that of immediate-release tablet
Announcements DRUG DESIGN DEVELOPMENT AND THERAPY Date of publication 201801
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29872264/
Education / Career
Article A non-linear pharmacokinetic-pharmacodynamic relationship of metformin in healthy volunteers: An open-label, parallel group, randomized clinical study
Announcements PLOS ONE Date of publication 201801
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29342199/
Education / Career
Article Assessment of Hepatic Cytochrome P450 3A Activity Using Metabolic Markers in Patients with Renal Impairment
Announcements JOURNAL OF KOREAN MEDICAL SCIENCE Date of publication 201801
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30595680/
Education / Career
Article Ursodeoxycholic acid improves liver function via phenylalanine/tyrosine pathway and microbiome remodelling in patients with liver dysfunction
Announcements SCIENTIFIC REPORTS Date of publication 201801
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30089798/
Education / Career
Article Active maintenance of endothelial cells prevents kidney fibrosis
Announcements Kidney Research and Clinical Practice Date of publication 201712
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29285425/
Education / Career
Article Risk factors for suboptimal drug concentration of posaconazole oral suspension in patients with hematologic malignancy
Announcements JOURNAL DE MYCOLOGIE MEDICALE Date of publication 201712
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28867258/
Education / Career
Article Pharmacokinetics and tolerability of MB12066, a beta-lapachone derivative targeting NAD(P)H: quinone oxidoreductase 1: two independent, double-blind, placebo-controlled, combined single and multiple ascending dose first-in-human clinical trials
Announcements DRUG DESIGN DEVELOPMENT AND THERAPY Date of publication 201711
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29158665/
Education / Career
Article Performance of the Minto model for the target-controlled infusion of remifentanil during cardiopulmonary bypass
Announcements ANAESTHESIA Date of publication 201710
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28891056/
Education / Career
Article An Accelerator Mass Spectrometry-Enabled Microtracer Study to Evaluate the First-Pass Effect on the Absorption of YH4808
Announcements CLINICAL PHARMACOLOGY & THERAPEUTICS Date of publication 201709
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28214288/
Education / Career
Article The Effect of Genetic Polymorphisms in SLCO2B1 on the Lipid-Lowering Efficacy of Rosuvastatin in Healthy Adults with Elevated Low-Density Lipoprotein
Announcements BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY Date of publication 201709
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28627804/
Education / Career
Article Urinary Metabolomic Signatures in Obstructive Sleep Apnea through Targeted Metabolomic Analysis: A Pilot Study
Announcements METABOLOMICS Date of publication 201708
Co-researcher
Education / Career
Article LBEC0101, A Proposed Etanercept Biosimilar: Pharmacokinetics, Immunogenicity, and Tolerability Profiles Compared with a Reference Biologic Product in Healthy Male Subjects
Announcements BIODRUGS Date of publication 201708
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28551775/
Education / Career
Article A novel K plus competitive acid blocker, YH4808, sustains inhibition of gastric acid secretion with a faster onset than esomeprazole: randomised clinical study in healthy volunteers
Announcements ALIMENTARY PHARMACOLOGY & THERAPEUTICS Date of publication 201708
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28543183/
Education / Career
Article Integrative Analysis of Renal Ischemia/Reperfusion Injury and Remote Ischemic Preconditioning in Mice
Announcements JOURNAL OF PROTEOME RESEARCH Date of publication 201707
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28627174/
Education / Career
Article Distribution of Exogenous and Endogenous CYP3A Markers and Related Factors in Healthy Males and Females
Announcements AAPS JOURNAL Date of publication 201707
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28523515/
Education / Career
Article Plasma LTE4/PGF(2 alpha) Ratio and Blood Eosinophil Count Are Increased in Elderly Asthmatics With Previous Asthma Exacerbation
Announcements ALLERGY ASTHMA & IMMUNOLOGY RESEARCH Date of publication 201707
Co-researcher
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28497926/

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