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Oh, Jaeseong
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Education / Career
Article Effects of food and race on the pharmacokinetics of lazertinib in healthy subjects and patients with EGFR mutation-positive advanced non-small cell lung cancer
Announcements Lung Cancer Date of publication 202301
Co-researcher Ki Young Huh, Yeji Lim, Deok Yong Yoon, Jun Gi Hwang, Sujin Sim, Jiah Kang, Jangyoung Wang, Mikyung Kim, Seong Bok Jang, S Martin Shreeve, Jaydeep Mehta 5, Nahor Haddish-Berhane, Jaeseong Oh, SeungHwan Lee, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36495784/
Education / Career
Article Dose-dependent glucosuria of DWP16001, a novel selective sodium-glucose cotransporter-2 inhibitor, in healthy subjects
Announcements Br J Clin Pharmacol Date of publication 202209
Co-researcher Jun Gi Hwang, Seung Hwan Lee, Wan Huh, Jumi Han, Jaeseong Oh, In-Jin Jang, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35395697/
Education / Career
Article The pharmacokinetic, safety, and tolerability profiles of eslicarbazepine acetate are comparable between Korean and White subjects
Announcements Clin Transl Sci Date of publication 202209
Co-researcher Sejung Hwang, Soyoung Lee, Eunwoo Kim, Inyoung Hwang, Joo-Youn Cho, Jae-Yong Chung, In-Jin Jang, Jaeseong Oh
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35727711/
Education / Career
Article Clinical Evaluation of Digital Therapeutics: Present and Future
Announcements Healthc Inform Res Date of publication 202207
Co-researcher Ki Young Huh, Jaeseong Oh, SeungHwan Lee, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35982593/
Education / Career
Article Effects of CYP2C19 genetic polymorphisms on the pharmacokinetics of lacosamide in Korean patients with epilepsy
Announcements Epilepsia Date of publication 202211
Co-researcher Seon-Jae Ahn, Jaeseong Oh, Do-Yong Kim, Hyoshin Son, Sungeun Hwang, Hye-Rim Shin, Eun Young Kim, Han Sang Lee, Woo-Jin Lee, Jangsup Moon, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Ki-Young Jung, SeungHwan Lee, Kyung-Sang Yu, Kon Chu, Sang Kun Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36039802/
Education / Career
Article Safety, tolerability, pharmacokinetic and pharmacodynamic characteristics of Vutiglabridin: a first-in-class, first-in-human study
Announcements Clin Transl Sci Date of publication 202211
Co-researcher Joo Young Na, Deok Yong Yoon, Hyounggyoon Yoo, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Sang-Ku Yoo, Youngah Kim, Jaeseong Oh
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36176051/
Education / Career
Article Dose-dependent reduction of lymphocyte count and heart rate after multiple administration of LC51-0255, a novel sphingosine-1-phosphate receptor 1 modulator, in healthy subjects
Announcements Front Pharmacol Date of publication 202208
Co-researcher Inyoung Hwang, Sang Won Lee, Jaeseong Oh, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36071831/
Education / Career
Article pharmacokinetics, safety and tolerability of valbenazine in Korean CYP2D6 normal and intermediate metabolizers
Announcements Clin Transl Sci Date of publication 202212
Co-researcher Woo Kyung Chung, Inyoung Hwang, Byungwook Kim, Jihyun Jung, Kyung-Sang Yu, In-Jin Jang, Jaeseong Oh
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36514192/
Education / Career
Article Pharmacokinetic evaluation of radiolabeled intraocular anti-CLEC14a antibody in preclinical animal species and application in humans
Announcements Clin Transl Sci Date of publication 202212
Co-researcher Sohyun Park, Youn Woo Lee, Jaeseong Oh, Su Jin Kim, Sukmook Lee, Ho-Young Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36129122/
Education / Career
Article Reversal of rocuronium-induced intense neuromuscular blockade by sugammadex in Korean children: A pharmacokinetic and pharmacodynamic analysis
Announcements Clin Transl Sci Date of publication 202210
Co-researcher Sang-Hwan Ji, Ki Young Huh, Jaeseong Oh, Hee-Jeong Jeong, Young-Eun Jang, Eun-Hee Kim, Ji-Hyun Lee, Jin-Tae Kim, Hee-Soo Kim
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36181377/
Education / Career
Article Single-dose of LC51-0255, a selective S1P 1 receptor modulator, showed dose-dependent and reversible reduction of absolute lymphocyte count in humans
Announcements Clinical and translational science. Date of publication 202204
Co-researcher Sang Won Lee, Inyoung Hwang, Jaeseong Oh, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35045208/
Education / Career
Article Population pharmacokinetic analysis of sildenafil in term and preterm infants with pulmonary arterial hypertension
Announcements Sci Rep Date of publication 202205
Co-researcher Su-Jin Rhee, Seung Han Shin, Jaeseong Oh, Young Hwa Jung, Chang Won Choi, Han-Suk Kim, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35513541/
Education / Career
Article Key Considerations for Phase 2 or 3 Clinical Study Design of Anti-Inflammatory Agent for COVID-19 Treatment
Announcements Frontiers in pharmacology. Date of publication 202206
Co-researcher Yewon Park, Joo Young Na, Joo-Youn Cho, Jaeseong Oh, Su-Jin Rhee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35721224/
Education / Career
Article Therapeutic drug monitoring on the use of transplacental digoxin in fetal tachyarrhythmia: a case report
Announcements Transl Clin Pharmacol Date of publication 202206
Co-researcher Sae Im Jeong, Heejae Won, Ildae Song, Jaeseong Oh
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35800665/
Education / Career
Article Pharmacokinetic and Pharmacodynamic Characteristics of Tripegfilgrastim, a Pegylated G-CSF, in Pediatric Patients with Solid Tumors
Announcements Clin Pharmacol Ther Date of publication 202201
Co-researcher Soyoung Lee, Kyung Taek Hong, Seol Ju Moon, Jung Yoon Choi, Che Ry Hong, Hee Young Shin, Joo-Youn Cho, In-Jin Jang, Kyung-Sang Yu, Jaeseong Oh, Hyoung Jin Kang
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34605552/
Education / Career
Article Endogenous metabolic markers for predicting the activity of dihydropyrimidine dehydrogenase
Announcements Clin Transl Sci Date of publication 202205
Co-researcher Jihyun Kang, Andrew HyoungJin Kim, Inseung Jeon, Jaeseong Oh, In-Jin Jang, SeungHwan Lee, Joo-Youn Cho
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34863048/
Education / Career
Article Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing
Announcements Transplantation Date of publication 202110
Co-researcher Jihoon G Yoon, Seung Hwan Song, Sungkyoung Choi, Jaeseong Oh, In-Jin Jang, Young Jin Kim, Sanghoon Moon, Bong-Jo Kim, Yuri Cho, Hyo Kee Kim, Sangil Min, Jongwon Ha, Ho Sik Shin, Chul Woo Yang, Hye Eun Yoon, Jaeseok Yang, Min Goo Lee, Jae Berm Park, Myoung Soo Kim, the Korean Organ Transplantation Registry (KOTRY) study group
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33654003/
Education / Career
Article Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform
Announcements Transl Clin Pharmacol Date of publication 202109
Co-researcher Byungwook Kim, Deok Yong Yoon, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu, Joo-Youn Cho, Jaeseong Oh
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34621706/
Education / Career
Article Population Pharmacokinetic Modelling and Simulation to Determine the Optimal Dose of Nanoparticulated Sorafenib to the Reference Sorafenib
Announcements Pharmaceutics. Date of publication 202104
Co-researcher Ki Young Huh, Sejung Hwang, Sang Yeob Park, Hye Jung Lim, Miryung Jin, Jaeseong Oh, Kyung Sang Yu, Jae Yong Chung
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33925058/
Education / Career
Article Comparison of Pharmacokinetic, Pharmacodynamic and Tolerability Profiles of CKD-11101, Darbepoetin Alfa (NESP�) Biosimilar, to Those of NESP� After a Single Subcutaneous or Intravenous Administration to Healthy Subjects
Announcements Drug Des Devel Ther. Date of publication 202104
Co-researcher Inseung Jeon, Jaeseong Oh, Yu-Kyung Kwon, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33953543/
Education / Career
Article A pilot study to investigate the utility of NAT2 genotype-guided isoniazid monotherapy regimens in NAT2 slow acetylators
Announcements Pharmacogenetics and genomics. Date of publication 202104
Co-researcher Hyounggyoon Yoo, Sang Chun Ji , Joo-Youn Cho, Sang-Heon Kim , Jihoon G Yoon, Min Goo Lee, Kyung-Sang Yu , In-Jin Jang, Jaeseong Oh
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33165168/
Education / Career
Article Pharmacokinetic comparison between a fixed-dose combination of fimasartan/amlodipine/ hydrochlorothiazide 60/10/25 mg and a corresponding loose combination of fimasartan/amlodipine 60/25 mg and hydrochlorothiazide 25 mg in healthy subjects
Announcements Transl Clin Pharmacol Date of publication 202103
Co-researcher Jihyun Jung, Soyoung Lee, Jaeseong Oh, SeungHwan Lee, In-Jin Jang, Donghwan Lee, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33855001/
Education / Career
Article A meta-analysis: efficacy and safety of anti-epileptic drugs prescribed in Korea as monotherapy and adjunctive treatment for patients with focal epilepsy
Announcements Transl Clin Pharmacol. Date of publication 202103
Co-researcher JuYeun Jeon, Jaeseong Oh, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33854997/
Education / Career
Article Oral absorption of voriconazole is affected by SLCO2B1 c.*396T>C genetic polymorphism in CYP2C19 poor metabolizers
Announcements Pharmacogenomics J Date of publication 202012
Co-researcher Sang Won Lee, Jaeseong Oh, Andrew HyoungJin Kim , Sang Chun Ji, Sang-In Park , Seo Hyun Yoon, Jae-Young Chung, Kyung-Sang Yu, In-Jin Jang, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32461666/
Education / Career
Article Evaluation of the pharmacokinetics and food effects of a novel formulation tamsulosin 0.4 mg capsule compared with a 0.2 mg capsule in healthy male volunteers
Announcements Transl Clin Pharmacol Date of publication 202012
Co-researcher Mu Seong Ban, Yu Kyong Kim, Byungwook Kim, Jina Jung, Yong-il Kim, Jaeseong Oh, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33425801/
Education / Career
Article Pharmacodynamics of tegoprazan and revaprazan after single and multiple oral doses in healthy subjects
Announcements Aliment Pharmacol Ther Date of publication 202012
Co-researcher Jung Sunwoo, Sang Chun Ji, Jaeseong Oh, Mu Seong Ban, Ji Yeon Nam, Bongtae Kim, Geun Seog Song, Kyung-Sang Yu, In-Jin Jang , SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33131095/
Education / Career
Article Population Pharmacokinetic Analysis of Amikacin for Optimal Pharmacotherapy in Korean Patients with Nontuberculous Mycobacterial Pulmonary Disease
Announcements Antibiotics. Date of publication 202011
Co-researcher Xuanyou Jin, Jaeseong Oh, Joo-Youn Cho, SeungHwan Lee, Su-Jin Rhee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33172135/
Education / Career
Article Pharmacokinetics and Tolerability of LC28-0126, a Novel Necrosis Inhibitor, After Multiple Ascending Doses: A Phase I Randomized, Double-blind, Placebo-controlled Study in Healthy Male Subjects
Announcements Clinical therapeutics. Date of publication 202010
Co-researcher Eunwoo Kim , Inyoung Hwang, SeungHwan Lee, Jaeseong Oh, Hyewon Chung, Myungwon Jin, Soon Ha Kim, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32980184/
Education / Career
Article Development of a Pharmacokinetic Model Describing Neonatal Fc Receptor‐Mediated Recycling of HL2351, a Novel Hybrid Fc‐Fused Interleukin‐1 Receptor Antagonist, to Optimize Dosage Regimen
Announcements CPT Pharmacometrics Syst Pharmacol Date of publication 202010
Co-researcher Lien Ngo, Jaeseong Oh , Anhye Kim, Hyun-Moon Back , Won-Ho Kang, Jung-Woo Chae , Hwi-Yeol Yun, Howard Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32945613/
Education / Career
Article Pharmacokinetics of human antithrombin III concentrate in the immediate postoperative period after liver transplantation.
Announcements Br J Clin Pharmacol. Date of publication 202005
Co-researcher Kim BR, Oh J, Yu KS, Ryu HG.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31840271/
Education / Career
Article Safety, tolerability and pharmacokinetics and pharmacodynamics of HL2351, a novel hybrid fc-fused interleukin-1 receptor antagonist, in healthy subjects: A first-in-human study. Br J Clin Pharmacol.
Announcements Br J Clin Pharmacol. Date of publication 202002
Co-researcher Oh J, Huh KY, Cho YG, Cha JE, Kim SJ, Yoon SH, Park SS, Yoon H, Lee J, Lee H.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31658396/
Education / Career
Article Pharmacokinetics of high-dose carboplatin in children undergoing high-dose chemotherapy and autologous stem cell transplantation with BSA-based dosing.
Announcements Bone marrow transplantation. Date of publication 202001
Co-researcher Che Ry Hong, Hyoung Jin Kang, Seol Ju Moon, Jaeseong Oh, Kyung Taek Hong, Jung Yoon Choi, Kyung-Sang Yu, Hee Young Shin
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31462686/
Education / Career
Article Pharmacokinetic Characteristics and Limited Sampling Strategies for Therapeutic Drug Monitoring of Colistin in Patients With Multidrug-Resistant Gram-Negative Bacterial Infections.
Announcements Ther Drug Monit Date of publication 201902
Co-researcher Kim EJ, Oh J, Lee K, Yu KS, Chung JY, Hwang JH, Nam EY, Kim HS, Kim M, Park JS, Song KH, Kim ES, Song J, Kim HB.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30299430/
Education / Career
Article Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity.
Announcements Genomics Inform Date of publication 201809
Co-researcher Oh J, Yi S, Gu N, Shin D, Yu KS, Yoon SH, Cho JY, Jang IJ
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30309203/
Education / Career
Article Characteristics of sauna deaths in Korea in relation to different blood alcohol concentrations.
Announcements Forensic Sci Med Pathol. Date of publication 201809
Co-researcher Yang KM, Lee BW, Oh J, Yoo SH.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29926439/
Education / Career
Article Safety, tolerability, pharmacodynamics and pharmacokinetics of DWP14012, a novel potassium-competitive acid blocker, in healthy male subjects.
Announcements Aliment Pharmacol Ther. Date of publication 201807
Co-researcher Sunwoo J, Oh J, Moon SJ, Ji SC, Lee SH, Yu KS, Kim HS, Lee A, Jang IJ.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29863280/
Education / Career
Article Effect of plasma membrane monoamine transporter genetic variants on pharmacokinetics of metformin in humans.
Announcements Transl Clin Pharmacol. Date of publication 201806
Co-researcher Moon SJ, Oh J, Lee SH, Choi Y, Yu KS, Chung JY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32055553/
Education / Career
Article Evaluation of the effects of food on levodropropizine controlled-release tablet and its pharmacokinetic profile in comparison to that of immediate-release tablet.
Announcements Drug Des Devel Ther Date of publication 201805
Co-researcher Lee S, Nam KY, Oh J, Lee S, Cho SM, Choi YW, Cho JY, Lee BJ, Hong JH.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29872264/
Education / Career
Article A post hoc analysis of intra-subject coefficients of variation in pharmacokinetic measures to calculate optimal sample sizes for bioequivalence studies.
Announcements Transl Clin Pharmacol. Date of publication 201803
Co-researcher Chung I, Oh J, Lee S, Jang IJ, Lee Y, Chung JY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32055541/
Education / Career
Article Safety, Tolerability, and Pharmacokinetic Characteristics of a Novel Nonopioid Analgesic, VVZ-149 Injections in Healthy Volunteers: A First-in-Class, First-in-Human Study.
Announcements J Clin Pharmacol. Date of publication 201801
Co-researcher Oh J, Lee S, Kim A, Yoon J, Jang K, Lee DH, Cho S, Lee SR, Yu KS, Chung JY.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28815639/
Education / Career
Article Performance of the Minto model for the target-controlled infusion of remifentanil during cardiopulmonary bypass.
Announcements Anaesthesia Date of publication 201710
Co-researcher Cho YJ, Jo WY, Oh H, Koo CH, Oh J, Cho JY, Yu KS, Jeon Y, Kim TK.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28891056/
Education / Career
Article Prediction of serum theophylline concentrations and cytochrome P450 1A2 activity by analyzing urinary metabolites in preterm infants.
Announcements Br J Clin Pharmacol Date of publication 201706
Co-researcher Sohn JA, Kim HS, Oh J, Cho JY, Yu KS, Lee J, Shin SH, Lee JA, Choi CW, Kim EK, Kim BI, Park EA.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/27995649/
Education / Career
Article Effects of CYP2C19 Genetic Polymorphisms on PK/PD Responses of Omeprazole in Korean Healthy Volunteers
Announcements J Korean Med Sci. Date of publication 201705
Co-researcher Park S, Hyun YJ, Kim YR, Lee JH, Ryu S, Kim JM, Oh WY, Na HS, Lee JG, Seo DW, Hwang IY, Park Z, Jang IJ, Oh J, Choi SE.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28378544/
Education / Career
Article The novel carboxylesterase 1 variant c.662A>G may decrease the bioactivation of oseltamivir in humans.
Announcements PLoS One. Date of publication 201704
Co-researcher Oh J, Lee S, Lee H, Cho JY, Yoon SH, Jang IJ, Yu KS, Lim KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28437488/
Education / Career
Article Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers.
Announcements Drug Des Devel Ther Date of publication 201703
Co-researcher Jang K, Kim MK, Oh J, Lee S, Cho JY, Yu KS, Choi TK, Lee SH, Lim KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28331290/
Education / Career
Article Effects of renal impairment on the pharmacokinetics and pharmacodynamics of a novel dipeptidyl peptidase-4 inhibitor, evogliptin (DA-1229).
Announcements Diabetes Obes Metab. Date of publication 201702
Co-researcher Oh J, Kim AH, Lee S, Cho H, Kim YS, Bahng MY, Yoon SH, Cho JY, Jang IJ, Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/27761990/
Education / Career
Article Pharmacokinetic and pharmacodynamic interactions between metformin and a novel dipeptidyl peptidase-4 inhibitor, evogliptin, in healthy subjects.
Announcements Drug Des Devel Ther Date of publication 201608
Co-researcher Rhee SJ, Choi Y, Lee S, Oh J, Kim SJ, Yoon SH, Cho JY, Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/27570447/
Education / Career
Article Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs.
Announcements J Vis Exp Date of publication 201607
Co-researcher Ahn SJ, Hong HK, Na YM, Park SJ, Ahn J, Oh J, Chung JY, Park KH, Woo SJ.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/27500363/
Education / Career
Article Evaluation of factors associated with drug-induced liver injury using electronic medical records.
Announcements Transl Clin Pharmacol. Date of publication 201606
Co-researcher Chung H, An H, Lee J, Oh J, Yu KS, Chung JY.
Education / Career
Article Inhibition of the multidrug and toxin extrusion (MATE) transporter by pyrimethamine increases the plasma concentration of metformin but does not increase antihyperglycaemic activity in humans.
Announcements Diabetes Obes Metab. Date of publication 201601
Co-researcher Oh J, Chung H, Park SI, Yi SJ, Jang K, Kim AH, Yoon J, Cho JY, Yoon SH, Jang IJ, Yu KS, Chung JY.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/26381793/

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