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HONGSEOK YUN
Department

1   Department of Genomic Medicine

2   Center for Precision Medicine

Specialty

1   Genomic Medicine , Precision Medicine , Genetic analysis

2   Precision Medicine

Appointment

Education / Career

Education / Career
Article Prediction of metabolites associated with somatic mutations in cancers by using genome-scale metabolic models and mutation data
Announcements Genome Biol Date of publication 2024-03
Co-researcher Lee G, Lee SM, Lee S, Jeong CW, Song H, Lee SY, Yun H, Koh Y, Kim HU
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38468344/
ETC URL https://pubmed.ncbi.nlm.nih.gov/38468344/
Education / Career
Article Multiple Primary Cancers With Hematologic Malignancies and Germline Predisposition: A Case Series
Announcements Ann Lab Med Date of publication 2024-03
Co-researcher Yun J, Lee DS, Lee S, Yun H
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/38449380/
ETC URL https://pubmed.ncbi.nlm.nih.gov/38449380/
Education / Career
Article Methylation-based Subclassifications of Embryonal Tumor with Multilayered Rosettes in Not Just Pediatric Brains
Announcements Exp Neurobiol Date of publication 2023-08
Co-researcher Kim EE, Lee K, Phi JH, Kim MS, Kang HJ, Yun H, Park SH
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/37927133/
ETC URL https://pubmed.ncbi.nlm.nih.gov/37927133/
Education / Career
Article Distinct mutational pattern of T-cell large granular lymphocyte leukemia combined with pure red cell aplasia: low mutational burden of STAT3
Announcements Sci Rep Date of publication 2023-05
Co-researcher Park S, Yun J, Choi SY, Jeong D, Gu JY, Lee JS, Seong MW, Chang YH, Yun H, Kim HK
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/37142644/
ETC URL https://pubmed.ncbi.nlm.nih.gov/37142644/
Education / Career
Article Genomic profiles of IDH-mutant gliomas: MYCN-amplified IDH-mutant astrocytoma had the worst prognosis
Announcements Sci Rep Date of publication 2023-04
Co-researcher Lee K, Kim SI, Kim EE, Shim YM, Won JK, Park CK, Choi SH, Yun H, Lee H, Park SH
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/37185778/
ETC URL https://pubmed.ncbi.nlm.nih.gov/37185778/
Education / Career
Article Expanding the Clinicopathologic Spectrum of YAP1::MAML2-Rearranged Thymic Neoplasm
Announcements Mod Pathol Date of publication 2023-02
Co-researcher Kim EE, Suh YY, Lee SW, Bae JM, Lee K, Lee S, Yun H, Jung KC, Koh J
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36853792/
ETC URL https://pubmed.ncbi.nlm.nih.gov/36853792/
Education / Career
Article Analysis of clinical and genomic profiles of therapy-related myeloid neoplasm in Korea
Announcements Hum Genomics Date of publication 2023-02
Co-researcher Yun J, Song H, Kim SM, Kim S, Kwon SR, Lee YE, Jeong D, Park JH, Kwon S, Yun H, Lee DS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36814285/
ETC URL https://pubmed.ncbi.nlm.nih.gov/36814285/
Education / Career
Article ITDetect: a method to detect internal tandem duplication of FMS-like tyrosine kinase (FLT3) from next-generation sequencing data with high sensitivity and clinical application
Announcements BMC Bioinformatics Date of publication 2023-02
Co-researcher Lee S, Sun CH, Jang H, Kim D, Yoon SS, Koh Y, Na SC, Cho SI, Kim MJ, Seong MW, Byun JM, Yun H
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36823555/
ETC URL https://pubmed.ncbi.nlm.nih.gov/36823555/
Education / Career
Article Mitigating the BFL1-mediated antiapoptotic pathway in diffuse large B cell lymphoma by inhibiting HDACs
Announcements Leuk Lymphoma Date of publication 2023-01
Co-researcher Park E, Lee C, Park J, Liu J, Hong J, Shin DY, Byun JM, Yun H, Koh Y, Yoon SS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36331521/
ETC URL https://pubmed.ncbi.nlm.nih.gov/36331521/
Education / Career
Article Transcriptional signatures of the BCL2 family for individualized acute myeloid leukaemia treatment
Announcements Genome Med Date of publication 2022-09
Co-researcher Lee C, Lee S, Park E, Hong J, Shin DY, Byun JM, Yun H, Koh Y, Yoon SS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36171613/
ETC URL https://pubmed.ncbi.nlm.nih.gov/36171613/
Education / Career
Article Pediatric-Type Indolent B-Cell Lymphomas With Overlapping Clinical, Pathologic, and Genetic Features
Announcements Am J Surg Pathol Date of publication 2022-08
Co-researcher Lim S, Lim KY, Koh J, Bae JM, Yun H, Lee C, Kim YA, Paik JH, Jeon YK
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35834399/
ETC URL https://pubmed.ncbi.nlm.nih.gov/35834399/
Education / Career
Article The telomere maintenance mechanism spectrum and its dynamics in gliomas
Announcements Genome Med Date of publication 2022-08
Co-researcher Kim S, Chowdhury T, Yu HJ, Kahng JY, Lee CE, Choi SA, Kim KM, Kang H, Lee JH, Lee ST, Won JK, Kim KH, Kim MS, Lee JY, Kim JW, Kim YH, Kim TM, Choi SH, Phi JH, Shin YK, Ku JL, Lee S, Yun H, Lee H, Kim D, Kim K, Hur JK, Park SH, Kim SK, Park CK
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35953846/
ETC URL https://pubmed.ncbi.nlm.nih.gov/35953846/
Education / Career
Article Clinicopathologic and Genetic Features of Primary T-cell Lymphomas of the Central Nervous System: An Analysis of 11 Cases Using Targeted Gene Sequencing
Announcements Am J Surg Pathol Date of publication 2022-04
Co-researcher Yim J, Koh J, Kim S, Song SG, Bae JM, Yun H, Sung JY, Kim TM, Park SH, Jeon YK
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34980830/
ETC URL https://pubmed.ncbi.nlm.nih.gov/34980830/
Education / Career
Article Consistent count region-copy number variation (CCR-CNV): an expandable and robust tool for clinical diagnosis of copy number variation at the exon level using next-generation sequencing data
Announcements Genet Med Date of publication 2022-03
Co-researcher Kim MJ, Lee S, Yun H, Cho SI, Kim B, Lee JS, Chae JH, Sun C, Park SS, Seong MW
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34906491/
ETC URL https://pubmed.ncbi.nlm.nih.gov/34906491/
Education / Career
Article An unusual case of microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR) diffuse large B-cell lymphoma revealed by targeted gene sequencing
Announcements J Pathol Transl Med Date of publication 2022-03
Co-researcher Han B, Kim S, Koh J, Bae JM, Yun H, Jeon YK
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34775735/
ETC URL https://pubmed.ncbi.nlm.nih.gov/34775735/
Education / Career
Article Genetic profile of primary plasma cell leukemia in Korea: comparison with plasma cell myeloma. Leuk Lymphoma
Announcements Leuk Lymphoma Date of publication 2022-02
Co-researcher Lee Y, Yun J, Jeong D, Ryu S, Kwon SR, Yun H, Kim SM, Park JH, Lee DS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34592901/
ETC URL https://pubmed.ncbi.nlm.nih.gov/34592901/
Education / Career
Article Sporadic and Lynch syndrome-associated mismatch repair-deficient brain tumors
Announcements Lab Invest Date of publication 2022-02
Co-researcher Kim H, Lim KY, Park JW, Kang J, Won JK, Lee K, Shim Y, Park CK, Kim SK, Choi SH, Kim TM, Yun H, Park SH
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34848827/
ETC URL https://pubmed.ncbi.nlm.nih.gov/34848827/
Education / Career
Article Recommendations for the Use of Next-Generation Sequencing and the Molecular Tumor Board for Patients with Advanced Cancer: A Report from KSMO and KCSG Precision Medicine Networking Group
Announcements Cancer Res Treat Date of publication 2022-01
Co-researcher Yoon S, Kim M, Hong YS, Kim HS, Kim ST, Kim J, Yun H, Yoo C, Ahn HK, Kim HS, Lee IH, Kim IH, Park I, Jeong JH, Cheon J, Kim JW, Yun J, Lim SM, Cha Y, Jang SJ, Zang DY, Kim TW, Kang JH, Kim JH
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34902959/
ETC URL https://pubmed.ncbi.nlm.nih.gov/34902959/
Education / Career
Article ZFTA-YAP1 fusion-positive ependymoma can occur in the spinal cord: Letter to the editor
Announcements Brain Pathol Date of publication 2022-01
Co-researcher Lim KY, Lee KH, Phi JH, Yun H, Won JK, Choi SH, Park SH
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34506076/
ETC URL https://pubmed.ncbi.nlm.nih.gov/34506076/
Education / Career
Article Molecular subtyping of ependymoma and prognostic impact of Ki-67
Announcements Brain Tumor Pathol Date of publication 2022-01
Co-researcher Lim KY, Lee K, Shim Y, Park JW, Kim H, Kang J, Won JK, Kim SK, Phi JH, Park CK, Chung CK, Yun H, Park SH
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34812989/
ETC URL https://pubmed.ncbi.nlm.nih.gov/34812989/
Education / Career
Article Revisiting vimentin: a negative surrogate marker of molecularly defined oligodendroglioma in adult type diffuse glioma
Announcements Brain Tumor Pathol Date of publication 2021-10
Co-researcher Kim SI, Lee K, Bae J, Lee S, Yun H, Park CK, Choi SH, Maquiling CA, Park SH, Won JK
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34338912/
ETC URL https://pubmed.ncbi.nlm.nih.gov/34338912/
Education / Career
Article Clinical and Genomic Characteristics of Adult Diffuse Midline Glioma
Announcements Cancer Res Treat Date of publication 2021-04
Co-researcher 26. Park C, Kim TM, Bae JM, Yun H, Kim JW, Choi SH, Lee ST, Lee JH, Park SH, Park CK
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33171023/
ETC URL https://pubmed.ncbi.nlm.nih.gov/33171023/
Education / Career
Article Proper Read Filtering Method to Adequately Analyze Whole-Transcriptome Sequencing and RNA Based Immune Repertoire Sequencing Data for Tumor Milieu Research
Announcements Cancers (Basel) Date of publication 2020/12
Co-researcher Lee S, Song S, Yoon SS, Koh Y, Yun H
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33317041/
Education / Career
Article Clinical and Genomic Characteristics of Adult Diffuse Midline Glioma
Announcements Cancer Res Treat Date of publication 2020/09
Co-researcher Park C, Kim TM, Bae JM, Yun H, Kim JW, Choi SH, Lee ST, Lee JH, Park SH, Park CK
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33171023/
Education / Career
Article MED-TMA: A clinical decision support tool for differential diagnosis of TMA with enhanced accuracy using an ensemble method
Announcements Thromb Res Date of publication 2020/09
Co-researcher Yoon J, Lee S, Sun CH, Kim D, Kim I, Yoon SS, Oh D, Yun H, Koh Y
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32622194/
Education / Career
Article Liquid biopsy-based tumor profiling for metastatic colorectal cancer patients with ultra-deep targeted sequencing
Announcements PLoS One Date of publication 2020/05
Co-researcher Kang JK, Heo S, Kim HP, Song SH, Yun H, Han SW, Kang GH, Bang D, Kim TY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32379795/
Education / Career
Article NPM1 as a potential therapeutic target for atypical teratoid/rhabdoid tumors
Announcements BMC Cancer Date of publication 2019/08
Co-researcher Phi JH, Sun CH, Lee SH, Lee S, Park I, Choi SA, Park SH, Lee JY, Wang KC, Kim SK, Yun H, Park CK
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31462227/
Education / Career
Article RTK-RAS pathway mutation is enriched in myeloid sarcoma
Announcements Blood Cancer J Date of publication 2018/05
Co-researcher Choi M, Jeon YK, Sun CH, Yun HS, Hong J, Shin DY, Kim I, Yoon SS, Koh Y
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29789584/
Education / Career
Article Genetic Characteristics of Polycythemia Vera and Essential Thrombocythemia in Korean Patients
Announcements J Clin Lab Anal Date of publication 2016/11
Co-researcher Yoo EH, Park KJ, Won HH, Park JH, Park JH, Lee ST, Kim HJ, Bang SM, Chi HS, Jung CW, Kim SH, Yun H, Sun CH, Park I, Lee S, Lee C, Merriman B, Luo R, Tan EH, Park KJ, Yoo NK, Kang JJ, Kim J
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/27132877/
Education / Career
Article A scientific treatment approach for acute mast cell leukemia: using a strategy based on next-generation sequencing data
Announcements Blood Res Date of publication 2016/03
Co-researcher Youk J, Koh Y, Kim JW, Kim DY, Park H, Jung WJ, Ahn KS, Yun H, Park I, Sun CH, Lee S, Yoon SS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/27104187/
Education / Career
Article Integrated genomic analyses identify frequent gene fusion events and VHL inactivation in gastrointestinal stromal tumors
Announcements Oncotarget Date of publication 2016/02
Co-researcher Kang G, Yun H, Sun CH, Park I, Lee S, Kwon J, Do I, Hong ME, Van Vrancken M, Lee J, Park JO, Cho J, Kim KM, Sohn TS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/25987131/
Education / Career
Article Genomic dynamics associated with malignant transformation in IDH1 mutated gliomas
Announcements Oncotarget Date of publication 2015/12
Co-researcher Park CK, Park I, Lee S, Sun CH, Koh Y, Park SH, Kim JE, Yun H, Lee SH
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/26524630/
Education / Career
Article Detection of a Distinctive Genomic Signature in Rhabdoid Glioblastoma, A Rare Disease Entity Identified by Whole Exome Sequencing and Whole Transcriptome Sequencing
Announcements Transl Oncol Date of publication 2015/08
Co-researcher Koh Y, Park I, Sun CH, Lee S, Yun H, Park CK, Park SH, Park JK, Lee SH
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/26310374/
Education / Career
Article Revising a Personal Genome by Comparing and Combining Data from Two Different Sequencing Platforms
Announcements PLoS One Date of publication 2013/04
Co-researcher Kim D, Kim WY, Lee SY, Lee SY, Yun H, Shin SY, Lee J, Hong Y, Won Y, Kim SJ, Lee YS, Ahn SM
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/23593254/
Education / Career
Article Genome-wide identification of the subcellular localization of the Escherichia coli B proteome using experimental and computational methods
Announcements Proteomics Date of publication 2011/04
Co-researcher Han MJ, Yun H, Lee JW, Lee YH, Lee SY, Yoo JS, Kim JY, Kim JF, Hur CG
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/21337514/
Education / Career
Article The genome-scale metabolic network analysis of Zymomonas mobilis ZM4 explains physiological features and suggests ethanol and succinic acid production strategies
Announcements Microb Cell Fact Date of publication 2010-11
Co-researcher Lee KY, Park JM, Kim TY, Yun H, Lee SY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/21092328/
Education / Career
Article Prediction of novel synthetic pathways for the production of desired chemicals
Announcements BMC Syst Biol Date of publication 2010-03
Co-researcher Cho A, Yun H, Park JH, Lee SY, Park S
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/20346180/
Education / Career
Article Microbial small heat shock proteins and their use in biotechnology
Announcements biotechadv Date of publication 2008-11
Co-researcher Han MJ, Yun H, Lee SY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/18789382/
Education / Career
Article Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network
Announcements Appl Microbiol Biotechnol Date of publication 2008-10
Co-researcher Lee J, Yun H, Feist AM, Palsson BO, Lee SY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/18758767/
Education / Career
Article EcoProDB: The Escherichia coli protein database
Announcements Bioinformatics Date of publication 2007-09
Co-researcher Yun H, Lee JW, Jeong J, Chung J, Park JM, Myoung HN, Lee SY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/17623702/
Education / Career
Article MFAML: A standard data structure for representing and exchanging metabolic flux models
Announcements Bioinformatics Date of publication 2005-08
Co-researcher Yun H, Lee DY, Jeong J, Lee S, Lee SY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/15905275/
Education / Career
Article MetaFluxNet: The management of metabolic reaction information and quantitative metabolic flux analysis
Announcements Bioinformatics Date of publication 2003-11
Co-researcher Lee DY, Yun H, Park S, Lee SY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/14594721/

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