張仁鎭
Department
临床药理学科
Specialty
网上预约
Pharmacogenomics
,
Clinical drug development
,
Drug Side Effects
,
Therapeutic drug monitoring
Education / Career
| Article | Coadministration of Voriconazole and Rifabutin Can Increase the Risk of Adverse Drug Reactions in Patients with Multiple Infections | ||
|---|---|---|---|
| Announcements | Ther Drug Monit | Date of publication | 202504 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/39023363/ | ||
| Article | Phase 1 studies of the safety, tolerability, pharmacokinetics, and pharmacodynamics of BI 690517 (vicadrostat), a novel aldosterone synthase inhibitor, in healthy male volunteers | ||
|---|---|---|---|
| Announcements | Naunyn Schmiedebergs Arch Pharmacol | Date of publication | 202502 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/39899058/ | ||
| Article | Population pharmacokinetic and pharmacodynamic model of evogliptin: Severe uremia increases the bioavailability of evogliptin | ||
|---|---|---|---|
| Announcements | CPT Pharmacometrics Syst Pharmacol | Date of publication | 202502 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/39465597/ | ||
| Article | Comparing haploidentical transplantation with post-transplantation cyclophosphamide and umbilical cord blood transplantation using targeted busulfan in children and adolescents with hematologic malignancies | ||
|---|---|---|---|
| Announcements | Blood Res | Date of publication | 202501 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/39847190/ | ||
| Article | Safety, Tolerability and Pharmacokinetics of Intravenous Sodium Taurodeoxycholate, HY209, a GPCR19 Agonist Inhibiting Inflammasomal Activation | ||
|---|---|---|---|
| Announcements | Drug Des Devel Ther | Date of publication | 202412 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/39670278/ | ||
| Article | Prospective phase II study of allogeneic hematopoietic stem cell transplantation with targeted busulfan, fludarabine, and etoposide conditioning in pediatric acute lymphoblastic leukemia | ||
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| Announcements | Hemasphere | Date of publication | 202411 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/39619243/ | ||
| Article | Pharmacokinetics and Pharmacodynamics of a Fixed-Dose Combination of Esomeprazole and Magnesium Hydroxide Compared to the Enteric-Coated Esomeprazole | ||
|---|---|---|---|
| Announcements | Clin Ther | Date of publication | 202411 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/39289057/ | ||
| Article | Pharmacokinetics, pharmacodynamics, safety, and tolerability of a single-dose riliprubart, an anti-C1s humanized monoclonal antibody in East-Asian adults: results from a Phase 1, randomized, open-label trial | ||
|---|---|---|---|
| Announcements | Expert Opin Investig Drugs | Date of publication | 202410 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/39171350/ | ||
| Article | Pharmacokinetic Interactions Between the Fixed-Dose Combination of Ezetimibe/Rosuvastatin 10/20 Mg and the Fixed-Dose Combination of Telmisartan/Amlodipine 80/5 Mg in Healthy Subjects | ||
|---|---|---|---|
| Announcements | Drug Des Devel Ther | Date of publication | 202407 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/38974125/ | ||
| Article | Pharmacokinetic interactions between fexuprazan, a potassium-competitive acid blocker, and nonsteroidal anti-inflammatory drugs in healthy males | ||
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| Announcements | Clin Transl Sci | Date of publication | 202405 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/38700290/ | ||
| Article | Estimation of the benefit from pre-emptive genotyping based on the nationwide cohort data in South Korea | ||
|---|---|---|---|
| Announcements | Clin Transl Sci | Date of publication | 202403 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/38501281/ | ||
| Article | Effects of meal type on the bioavailability of vutiglabridin, a novel anti-obesity agent, in healthy subjects | ||
|---|---|---|---|
| Announcements | Clin Transl Sci | Date of publication | 202403 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/38436494/ | ||
| Article | Synergistic toxicity with copper contributes to NAT2-associated isoniazid toxicity | ||
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| Announcements | Exp Mol Med | Date of publication | 202403 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/38424191/ | ||
| Article | Pharmacokinetic Comparison Between a Fixed-Dose Combination of Atorvastatin/Omega-3-Acid Ethyl Esters and the Corresponding Loose Combination in Healthy Korean Male Subjects | ||
|---|---|---|---|
| Announcements | Drug Des Devel Ther | Date of publication | 202402 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/38352172/ | ||
| Article | Evaluation of Food Effect on the Pharmacokinetics of Velufenacin, a New Muscarinic Receptor Antagonist, in Healthy Subjects | ||
|---|---|---|---|
| Announcements | Clin Pharmacol Drug Dev | Date of publication | 202402 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/38156730/ | ||
| Article | Effects of food and ethnicity on the pharmacokinetics of venadaparib, a next-generation PARP inhibitor, in healthy Korean, Caucasian, and Chinese male subjects | ||
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| Announcements | Invest New Drugs | Date of publication | 202402 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/38099989/ | ||
| Article | Topiramate dosage optimization for effective antiseizure management via population pharmacokinetic modeling | ||
|---|---|---|---|
| Announcements | Ann Clin Transl Neurol | Date of publication | 202402 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/38062636/ | ||
| Article | Immunogenicity and safety of SARS-CoV-2 recombinant protein nanoparticle vaccine GBP510 adjuvanted with AS03: interim results of a randomised, active-controlled, observer-blinded, phase 3 trial | ||
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| Announcements | EClinicalMedicine | Date of publication | 202309 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/37711219/ | ||
| Article | Semimechanistic pharmacokinetic-pharmacodynamic model of tripegfilgrastim for pediatric patients after chemotherapy | ||
|---|---|---|---|
| Announcements | CPT Pharmacometrics Syst Pharmacol | Date of publication | 202309 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/37559343/ | ||
| Article | Pharmacokinetic and pharmacodynamic exploration of various combinations of tegoprazan immediate and delayed-release formulations | ||
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| Announcements | Br J Clin Pharmacol | Date of publication | 202309 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/37170677/ | ||
| Article | Effect of Food on the Pharmacokinetics and Pharmacodynamics of a Novel Dual Delayed-Release Formulation of Esomeprazole in Healthy Subjects | ||
|---|---|---|---|
| Announcements | Clin Pharmacol Drug Dev | Date of publication | 202308 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/36929154/ | ||
| Article | Safety, tolerability, pharmacokinetic/pharmacodynamic characteristics of bersiporocin, a novel prolyl-tRNA synthetase inhibitor, in healthy subjects | ||
|---|---|---|---|
| Announcements | Clin Transl Sci | Date of publication | 202307 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/37095713/ | ||
| Article | Effect of haemodialysis on the pharmacokinetics and pharmacodynamics of evogliptin | ||
|---|---|---|---|
| Announcements | Diabetes Obes Metab | Date of publication | 202306 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/36852751/ | ||
| Article | Pharmacokinetic and Pharmacodynamic Interaction of DWP16001, an SGLT2 Inhibitor, with Gemigliptin and Metformin in Healthy Adults | ||
|---|---|---|---|
| Announcements | Br J Clin Pharmacol | Date of publication | 202306 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/36496349/ | ||
| Article | A Comparison of the Pharmacokinetics and Safety of Dapagliflozin Formate, an Ester Prodrug of Dapagliflozin, to Dapagliflozin Propanediol Monohydrate in Healthy Subjects | ||
|---|---|---|---|
| Announcements | Drug Des Devel Ther | Date of publication | 202304 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/37113469/ | ||
| Article | Pharmacokinetics and Pharmacodynamics of Esomezol DR, a New Dual Delayed-Release Formulation of Esomeprazole 20 Mg or 40 Mg, in Healthy Subjects | ||
|---|---|---|---|
| Announcements | Drug Des Devel Ther | Date of publication | 202304 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/37077412/ | ||
| Article | Evaluation of CYP2C19-Mediated Pharmacokinetic Drug Interaction of Tegoprazan, Compared with Vonoprazan or Esomeprazole | ||
|---|---|---|---|
| Announcements | Clin Pharmacokinet | Date of publication | 202304 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/36897544/ | ||
| Article | Pharmacokinetic and pharmacodynamic interaction between DWP16001, an sodium-glucose cotransporter 2 inhibitor and metformin in healthy subjects | ||
|---|---|---|---|
| Announcements | Br J Clin Pharmacol | Date of publication | 202304 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/36422809/ | ||
| Article | pharmacokinetics, safety and tolerability of valbenazine in Korean CYP2D6 normal and intermediate metabolizers | ||
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| Announcements | Clin Transl Sci | Date of publication | 202303 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/36514192/ | ||
| Article | Pharmacodynamic and Pharmacokinetic Drug Interactions between Fexuprazan, a Novel Potassium-Competitive Inhibitor, and Aspirin, in Healthy Subjects | ||
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| Announcements | Pharmaceutics | Date of publication | 202302 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/36839870/ | ||
| Article | Evaluation of drug prescribing patterns and therapeutic drug monitoring practice using electronic medical records | ||
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| Announcements | Sci Rep | Date of publication | 202212 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/36494483/ | ||
| Article | A database of 5305 healthy Korean individuals reveals genetic and clinical implications for an East Asian population | ||
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| Announcements | Exp Mol Med | Date of publication | 202211 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/36323850/ | ||
| Article | Safety, tolerability, pharmacokinetic and pharmacodynamic characteristics of Vutiglabridin: a first-in-class, first-in-human study | ||
|---|---|---|---|
| Announcements | Clin Transl Sci | Date of publication | 202211 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/36176051/ | ||
| Article | Safety, tolerability, and serum/tear pharmacokinetics of human recombinant epidermal growth factor eyedrops in healthy subjects | ||
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| Announcements | Pharmaceuticals (Basel) | Date of publication | 202210 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/36355484/ | ||
| Article | The pharmacokinetic, safety, and tolerability profiles of eslicarbazepine acetate are comparable between Korean and White subjects | ||
|---|---|---|---|
| Announcements | Clin Transl Sci | Date of publication | 202209 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/35727711/ | ||
| Article | Dose-dependent glucosuria of DWP16001, a novel selective sodium-glucose cotransporter-2 inhibitor, in healthy subjects | ||
|---|---|---|---|
| Announcements | Br J Clin Pharmacol | Date of publication | 202209 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/35395697/ | ||
| Article | Dose-dependent reduction of lymphocyte count and heart rate after multiple administration of LC51-0255, a novel sphingosine-1-phosphate receptor 1 modulator, in healthy subjects | ||
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| Announcements | Front Pharmacol | Date of publication | 202208 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/36071831/ | ||
| Article | Night-time gastric acid suppression by tegoprazan compared to vonoprazan or esomeprazole | ||
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| Announcements | British journal of clinical pharmacology. | Date of publication | 202207 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/35146797/ | ||
| Article | Comparative pharmacokinetics between two tablets of tramadol 37.5 mg/acetaminophen 325 mg and one tablet of tramadol 75 mg/acetaminophen 650 mg for extended-release fixed-dose combination | ||
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| Announcements | Transl Clin Pharmacol | Date of publication | 202206 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/35800670/ | ||
| Article | Single-dose of LC51-0255, a selective S1P 1 receptor modulator, showed dose-dependent and reversible reduction of absolute lymphocyte count in humans | ||
|---|---|---|---|
| Announcements | Clinical and translational science. | Date of publication | 202204 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/35045208/ | ||
| Article | A Phase 1 Study to Evaluate the Safety and Pharmacokinetics following Administration of Single and Multiple Doses of the Anti-Staphylococcal Lysin, LSVT-1701, in Healthy Adult Subjects | ||
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| Announcements | Antimicrobial agents and chemotherapy. | Date of publication | 202203 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/35007129/ | ||
| Article | Pharmacokinetic and Pharmacodynamic Characteristics of Tripegfilgrastim, a Pegylated G-CSF, in Pediatric Patients with Solid Tumors | ||
|---|---|---|---|
| Announcements | Clin Pharmacol Ther | Date of publication | 202201 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/34605552/ | ||
| Article | Comparative Pharmacokinetics/Pharmacodynamics of Fixed-Dose Combination of Esomeprazole and Calcium Carbonate (AD-206) to the Conventional Esomeprazole | ||
|---|---|---|---|
| Announcements | Drug design, development and therapy. | Date of publication | 202112 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/34992346/ | ||
| Article | Endogenous metabolic markers for predicting the activity of dihydropyrimidine dehydrogenase | ||
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| Announcements | Clin Transl Sci | Date of publication | 202112 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/34863048/ | ||
| Article | The necessary conduct: Exploratory multiregional clinical trials in East Asia | ||
|---|---|---|---|
| Announcements | Clin Transl Sci | Date of publication | 202111 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/34397152/ | ||
| Article | Pharmacokinetics of Ginsenoside Compound K From a Compound K Fermentation Product, CK-30, and From Red Ginseng Extract in Healthy Korean Subjects | ||
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| Announcements | Clin Pharmacol Drug Dev. | Date of publication | 202111 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33884767/ | ||
| Article | Pharmacokinetic Interaction Among Ezetimibe, Rosuvastatin, and Telmisartan | ||
|---|---|---|---|
| Announcements | Clin Pharmacol Drug Dev. | Date of publication | 202111 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33647189/ | ||
| Article | Pharmacokinetics and safety of cenobamate, a novel antiseizure medication, in healthy Japanese, and an ethnic comparison with healthy non-Japanese | ||
|---|---|---|---|
| Announcements | Clin Transl Sci | Date of publication | 202110 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/34670008/ | ||
| Article | Pharmacokinetics and safety of a novel influenza treatment (baloxavir marboxil) in Korean subjects compared with Japanese subjects | ||
|---|---|---|---|
| Announcements | Clin Transl Sci | Date of publication | 202110 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/34664769/ | ||
| Article | Unraveling the Genomic Architecture of the CYP3A Locus and ADME Genes for Personalized Tacrolimus Dosing | ||
|---|---|---|---|
| Announcements | Transplantation | Date of publication | 202110 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33654003/ | ||
| Article | Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform | ||
|---|---|---|---|
| Announcements | Transl Clin Pharmacol | Date of publication | 202109 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/34621706/ | ||
| Article | Prediction of Drug-Drug Interaction Potential of Tegoprazan Using Physiologically Based Pharmacokinetic Modeling and Simulation | ||
|---|---|---|---|
| Announcements | Pharmaceutics | Date of publication | 202109 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/34575565/ | ||
| Article | A phase I study to evaluate the safety, tolerability, pharmacodynamic and pharmacokinetic profiles of ocular GLH8NDE in healthy male adults | ||
|---|---|---|---|
| Announcements | Clin Transl Sci | Date of publication | 202109 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/34523814/ | ||
| Article | Changes in the gut microbiome influence the hypoglycemic effect of metformin through the altered metabolism of branched-chain and nonessential amino acids | ||
|---|---|---|---|
| Announcements | Diabetes Res Clin Pract | Date of publication | 202108 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/34329692/ | ||
| Article | Pharmacokinetic Equivalence of CT-P17 to High-Concentration (100 mg/mL) Reference Adalimumab: A Randomized Phase I Study in Healthy Subjects | ||
|---|---|---|---|
| Announcements | Clinical and translational science. | Date of publication | 202107 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33503313/ | ||
| Article | Pharmacokinetics, Tolerability and Pharmacogenetics of DA-8031 After Multiple Ascending Doses in Healthy Male Subjects | ||
|---|---|---|---|
| Announcements | Drug Design, Development and Therapy | Date of publication | 202106 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/34103898/ | ||
| Article | Effect of meal timing on pharmacokinetics and pharmacodynamics of tegoprazan in healthy male volunteers | ||
|---|---|---|---|
| Announcements | Clin Transl Sci | Date of publication | 202105 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33382926/ | ||
| Article | Comparison of Pharmacokinetic, Pharmacodynamic and Tolerability Profiles of CKD-11101, Darbepoetin Alfa (NESP�) Biosimilar, to Those of NESP� After a Single Subcutaneous or Intravenous Administration to Healthy Subjects | ||
|---|---|---|---|
| Announcements | Drug Des Devel Ther. | Date of publication | 202104 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33953543/ | ||
| Article | A pilot study to investigate the utility of NAT2 genotype-guided isoniazid monotherapy regimens in NAT2 slow acetylators | ||
|---|---|---|---|
| Announcements | Pharmacogenetics and genomics. | Date of publication | 202104 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33165168/ | ||
| Article | Safety, pharmacokinetics and pharmacodynamics of BI 655064 in phase 1 clinical trials in healthy Chinese and Japanese subjects | ||
|---|---|---|---|
| Announcements | Br J Clin Pharmacol | Date of publication | 202104 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33047859/ | ||
| Article | Pharmacokinetic comparison between a fixed-dose combination of fimasartan/amlodipine/ hydrochlorothiazide 60/10/25 mg and a corresponding loose combination of fimasartan/amlodipine 60/25 mg and hydrochlorothiazide 25 mg in healthy subjects | ||
|---|---|---|---|
| Announcements | Transl Clin Pharmacol | Date of publication | 202103 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33855001/ | ||
| Article | Population pharmacokinetic model development and its relationship with adverse events of oxcarbazepine in adult patients with epilepsy | ||
|---|---|---|---|
| Announcements | Sci Rep. | Date of publication | 202103 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33737678/ | ||
| Article | Pharmacokinetics and Safety of Extended-release Ranolazine in Korean and White Healthy Subjects | ||
|---|---|---|---|
| Announcements | Clinical therapeutics. | Date of publication | 202103 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33518355/ | ||
| Article | Pharmacokinetic and Pharmacodynamic Comparison of Two Formulations of a Fixed-Dose Combination of Gemigliptin/Rosuvastatin 50/20 mg: A Randomized, Open-Label, Single-Dose, Two-Way Crossover Study | ||
|---|---|---|---|
| Announcements | Drug Des Devel Ther | Date of publication | 202102 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33628012/ | ||
| Article | The utility of CYP3A activity endogenous markers for evaluating drug-drug interaction between sildenafil and CYP3A inhibitors in healthy subjects | ||
|---|---|---|---|
| Announcements | Drug Metab Pharmacokinet | Date of publication | 202102 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33348240/ | ||
| Article | Urinary metabolic markers reflect on hepatic, not intestinal, CYP3A activity in healthy subjects | ||
|---|---|---|---|
| Announcements | Drug Metab Pharmacokinet | Date of publication | 202102 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33348239/ | ||
| Article | Tolerability of lacosamide rapid dose titration: A randomized, multicenter, prospective, open-label study | ||
|---|---|---|---|
| Announcements | Epilepsy Behav | Date of publication | 202102 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33342710/ | ||
| Article | Effects of perampanel on cognition and quantitative electroencephalography in patients with epilepsy | ||
|---|---|---|---|
| Announcements | Epilepsy Behav | Date of publication | 202102 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33328106/ | ||
| Article | Electronic medical records-based comparison of glycemic control efficacy between sulfonylureas and dipeptidyl peptidase-4 inhibitors added on to metformin monotherapy in patients with type 2 diabetes | ||
|---|---|---|---|
| Announcements | TCP | Date of publication | 202012 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33425803/ | ||
| Article | Pharmacogenomic information from CPIC and DPWG guidelines and its application on drug labels | ||
|---|---|---|---|
| Announcements | Transl Clin Pharmacol | Date of publication | 202012 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33425802/ | ||
| Article | Effect of Meal Timing on Pharmacokinetics and Pharmacodynamics of Tegoprazan in Healthy Male volunteers | ||
|---|---|---|---|
| Announcements | Clin Transl Sci | Date of publication | 202012 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33382926/ | ||
| Article | Pharmacodynamics of tegoprazan and revaprazan after single and multiple oral doses in healthy subjects | ||
|---|---|---|---|
| Announcements | Aliment Pharmacol Ther | Date of publication | 202012 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33131095/ | ||
| Article | Pharmacodynamics and pharmacokinetics of DWP14012 (fexuprazan) in healthy subjects with different ethnicities | ||
|---|---|---|---|
| Announcements | Aliment Pharmacol Ther | Date of publication | 202012 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33111337/ | ||
| Article | Oral absorption of voriconazole is affected by SLCO2B1 c.*396T>C genetic polymorphism in CYP2C19 poor metabolizers | ||
|---|---|---|---|
| Announcements | Pharmacogenomics J | Date of publication | 202012 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32461666/ | ||
| Article | Pharmacokinetic/Pharmacodynamic Interactions Between Evogliptin and Glimepiride in Healthy Male Subjects | ||
|---|---|---|---|
| Announcements | Drug Des Devel The | Date of publication | 202011 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33262578/ | ||
| Article | Pharmacokinetic/Pharmacodynamic Interaction Between Evogliptin and Pioglitazone in Healthy Male Subjects | ||
|---|---|---|---|
| Announcements | Drug Des Devel The | Date of publication | 202010 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/33122892/ | ||
| Article | Impact of vancomycin-induced changes in the intestinal microbiota on the pharmacokinetics of simvastatin. | ||
|---|---|---|---|
| Announcements | Clin Transl Sci | Date of publication | 202007 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32058642/ | ||
| Article | Usefulness of saliva for perampanel therapeutic drug monitoring. in Epilepsia has the following publication status | ||
|---|---|---|---|
| Announcements | Epilepsia | Date of publication | 202006 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32378757/ | ||
| Article | Comparison of Pharmacokinetics of a Fixed-Dose Combination of Amlodipine/Losartan/Rosuvastatin With Concomitant Administration of Amlodipine/Losartan and Rosuvastatin in Healthy Volunteers | ||
|---|---|---|---|
| Announcements | Drug Des Devel Ther | Date of publication | 202002 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32109991/ | ||
| Article | Colorectal cancer diagnostic model utilizing metagenomic and metabolomic data of stool microbial extracellular vesicles. | ||
|---|---|---|---|
| Announcements | Scientific reports | Date of publication | 202002 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32071370/ | ||
| Article | Influence of OATP1B1 and BCRP polymorphisms on the pharmacokinetics and pharmacodynamics of rosuvastatin in elderly and young Korean subjects. | ||
|---|---|---|---|
| Announcements | Scientific reports | Date of publication | 201912 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31857620/ | ||
| Article | Influence of midazolam-related genetic polymorphism on conscious sedation during upper gastrointestinal endoscopy in a Korean population. | ||
|---|---|---|---|
| Announcements | Scientific reports. | Date of publication | 201911 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31690757/ | ||
| Article | Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from Cirrhosis | ||
|---|---|---|---|
| Announcements | Cancers | Date of publication | 201910 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31590436/ | ||
| Article | ST2 blockade mitigates peritoneal fibrosis induced by TGF-β and high glucose. | ||
|---|---|---|---|
| Announcements | J Cell Mol Med | Date of publication | 201910 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31397957/ | ||
| Article | Artificial intelligence in drug development: clinical pharmacologist perspective | ||
|---|---|---|---|
| Announcements | TCP | Date of publication | 201909 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/32055587/ | ||
| Article | Safety, tolerability, and anti-tumor activity of olmutinib in non-small cell lung cancer with T790M mutation: A single arm, open label, phase 1/2 trial. | ||
|---|---|---|---|
| Announcements | Lung cancer | Date of publication | 201909 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31447004/ | ||
| Article | Quantitative prediction of hepatic CYP3A activity using endogenous markers in healthy subjects after administration of CYP3A inhibitors or inducers. | ||
|---|---|---|---|
| Announcements | Drug metabolism and pharmacokinetics | Date of publication | 201908 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31088714/ | ||
| Article | Challenges and insights of early oncology drug development in the Asia-Pacific region: introduction of phase I oncology clinical trial center and experience sharing for early clinical trials in Seoul National University Hospital, Korea. | ||
|---|---|---|---|
| Announcements | Chinese clinical oncology. | Date of publication | 201906 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31311281/ | ||
| Article | A safety, pharmacokinetic, pharmacogenomic and population pharmacokinetic analysis of the third-generation EGFR TKI, olmutinib (HM61713), after single oral administration in healthy volunteers. | ||
|---|---|---|---|
| Announcements | Basic Clin Pharmacol Toxicol | Date of publication | 201905 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/31125491/ | ||
| Article | Comparison of the Plasma Metabolome Profiles Between the Internal Thoracic Artery and Ascending Aorta in Patients Undergoing Coronary Artery Bypass Graft Surgery Using Gas Chromatography Time-of-Flight Mass Spectrometry. | ||
|---|---|---|---|
| Announcements | Journal of Korean medical science (JKMS) | Date of publication | 201904 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/30950250/ | ||
| Article | Ursodeoxycholic acid exerts hepatoprotective effects by regulating amino acid, flavonoid, and fatty acid metabolic pathways | ||
|---|---|---|---|
| Announcements | Metabolomics Society | Date of publication | 201902 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/30830474/ | ||
| Article | A Personalized CYP2C19 Phenotype-Guided Dosing Regimen of Voriconazole Using a Population Pharmacokinetic Analysis | ||
|---|---|---|---|
| Announcements | Journal of clinical medicine | Date of publication | 201902 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/30744151/ | ||
| Article | Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity. | ||
|---|---|---|---|
| Announcements | Genomics & Informatics | Date of publication | 201811 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/30309203/ | ||
| Article | Favorable Outcome of Post-Transplantation Cyclophosphamide Haploidentical Peripheral Blood Stem Cell Transplantation with Targeted Busulfan-Based Myeloablative Conditioning Using Intensive Pharmacokinetic Monitoring in Pediatric Patients | ||
|---|---|---|---|
| Announcements | BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION | Date of publication | 201811 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/29981849/ | ||
| Article | Effect of food on the pharmacokinetics of YH4808, a potassium-competitive acid blocker, after single- and multiple-oral dosing in healthy subjects | ||
|---|---|---|---|
| Announcements | EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY | Date of publication | 201810 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/29907887/ | ||
| Article | Safety, tolerability, pharmacodynamics and pharmacokinetics of DWP14012, a novel potassium-competitive acid blocker, in healthy male subjects | ||
|---|---|---|---|
| Announcements | ALIMENTARY PHARMACOLOGY & THERAPEUTICS | Date of publication | 201807 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/29863280/ | ||
| Article | Assessment of induced CYP3A activity in pregnant women using 4 beta-hydroxycholesterol: Cholesterol ratio as an appropriate metabolic marker | ||
|---|---|---|---|
| Announcements | DRUG METABOLISM AND PHARMACOKINETICS | Date of publication | 201806 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/29759884/ | ||
| Article | The safety, tolerability and pharmacokinetics of BI 409306, a novel and potent PDE9 inhibitor: Overview of three Phase I randomised trials in healthy volunteers | ||
|---|---|---|---|
| Announcements | EUROPEAN NEUROPSYCHOPHARMACOLOGY | Date of publication | 201805 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/29567399/ | ||
| Article | Identification of - or (-1)-Hydroxylated Medium-Chain Acylcarnitines as Novel Urinary Biomarkers for CYP3A Activity | ||
|---|---|---|---|
| Announcements | CLINICAL PHARMACOLOGY & THERAPEUTICS | Date of publication | 201805 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/28877336/ | ||
| Article | Assessment of Appropriateness of an Initial Dosing Regimen of Vancomycin and Development of a New Dosing Nomogram | ||
|---|---|---|---|
| Announcements | BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY | Date of publication | 201802 |
| Co-researcher | |||
| Pubmed URL | https://www.ncbi.nlm.nih.gov/pubmed/28834212/ | ||