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李承桓
Department

临床药理学科

Specialty

Personalized Optimal Pharmacotherapy , Early clinical trial for drug development , Pharmacogenomics

网上预约

Education / Career

Education / Career
Article Effects of food and race on the pharmacokinetics of lazertinib in healthy subjects and patients with EGFR mutation-positive advanced non-small cell lung cancer
Announcements Lung Cancer Date of publication 202301
Co-researcher Ki Young Huh, Yeji Lim, Deok Yong Yoon, Jun Gi Hwang, Sujin Sim, Jiah Kang, Jangyoung Wang, Mikyung Kim, Seong Bok Jang, S Martin Shreeve, Jaydeep Mehta 5, Nahor Haddish-Berhane, Jaeseong Oh, SeungHwan Lee, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36495784/
Education / Career
Article Night-time gastric acid suppression by tegoprazan compared to vonoprazan or esomeprazole
Announcements British journal of clinical pharmacology. Date of publication 202207
Co-researcher Eunsol Yang, Seokuee Kim, Bongtae Kim, Boram Kim, Yechan Kim, Sung Sup Park, Geun Seog Song, Kyung-Sang Yu, In-Jin Jang, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35146797/
Education / Career
Article Dose-dependent glucosuria of DWP16001, a novel selective sodium-glucose cotransporter-2 inhibitor, in healthy subjects
Announcements Br J Clin Pharmacol Date of publication 202209
Co-researcher Jun Gi Hwang, Seung Hwan Lee, Wan Huh, Jumi Han, Jaeseong Oh, In-Jin Jang, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35395697/
Education / Career
Article Clinical Evaluation of Digital Therapeutics: Present and Future
Announcements Healthc Inform Res Date of publication 202207
Co-researcher Ki Young Huh, Jaeseong Oh, SeungHwan Lee, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35982593/
Education / Career
Article Effects of CYP2C19 genetic polymorphisms on the pharmacokinetics of lacosamide in Korean patients with epilepsy
Announcements Epilepsia Date of publication 202211
Co-researcher Seon-Jae Ahn, Jaeseong Oh, Do-Yong Kim, Hyoshin Son, Sungeun Hwang, Hye-Rim Shin, Eun Young Kim, Han Sang Lee, Woo-Jin Lee, Jangsup Moon, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Ki-Young Jung, SeungHwan Lee, Kyung-Sang Yu, Kon Chu, Sang Kun Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36039802/
Education / Career
Article Safety, tolerability, pharmacokinetic and pharmacodynamic characteristics of Vutiglabridin: a first-in-class, first-in-human study
Announcements Clin Transl Sci Date of publication 202211
Co-researcher Joo Young Na, Deok Yong Yoon, Hyounggyoon Yoo, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Sang-Ku Yoo, Youngah Kim, Jaeseong Oh
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36176051/
Education / Career
Article Dose-dependent reduction of lymphocyte count and heart rate after multiple administration of LC51-0255, a novel sphingosine-1-phosphate receptor 1 modulator, in healthy subjects
Announcements Front Pharmacol Date of publication 202208
Co-researcher Inyoung Hwang, Sang Won Lee, Jaeseong Oh, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36071831/
Education / Career
Article Considerations for clinical evaluation of the effects of bariatric surgery on the pharmacokinetics of orally administered drugs
Announcements Transl Clin Pharmacol Date of publication 202209
Co-researcher Sungyeun Bae, JungJin Oh, Ildae Song, Kyung-Sang Yu, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36247747/
Education / Career
Article Pharmacokinetic and pharmacodynamic interaction between DWP16001, an sodium-glucose cotransporter 2 inhibitor and metformin in healthy subjects
Announcements Br J Clin Pharmacol Date of publication 202211
Co-researcher Byungwook Kim, Ki Young Huh, Jun Gi Hwang, JaeJin Nah, Wan Huh, Jae Min Cho, In-Jin Jang, Kyung-Sang Yu, Yun Kim, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36422809/
Education / Career
Article A database of 5305 healthy Korean individuals reveals genetic and clinical implications for an East Asian population
Announcements Exp Mol Med Date of publication 202211
Co-researcher Jeongeun Lee, Jean Lee, Sungwon Jeon, Jeongha Lee, Insu Jang, Jin Ok Yang, Soojin Park, Byungwook Lee, Jinwook Choi, Byung-Ok Choi, Heon Yung Gee, Jaeseong Oh, In-Jin Jang, Sanghyuk Lee, Daehyun Baek, Youngil Koh, Sung-Soo Yoon, Young-Joon Kim, Jong-Hee Chae, Woong-Yang Park, Jong Hwa Bhak, Murim Choi
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36323850/
Education / Career
Article Pharmacokinetic and Pharmacodynamic Interaction of DWP16001, an SGLT2 Inhibitor, with Gemigliptin and Metformin in Healthy Adults
Announcements Br J Clin Pharmacol Date of publication 202212
Co-researcher Sae Im Jeong, Yun Kim, Jae Jin Nah, Wan Huh, In-Jin Jang, Jun Gi Hwang, Seung Hwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/36496349/
Education / Career
Article Single-dose of LC51-0255, a selective S1P 1 receptor modulator, showed dose-dependent and reversible reduction of absolute lymphocyte count in humans
Announcements Clinical and translational science. Date of publication 202204
Co-researcher Sang Won Lee, Inyoung Hwang, Jaeseong Oh, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35045208/
Education / Career
Article A Phase 1 Study to Evaluate the Safety and Pharmacokinetics following Administration of Single and Multiple Doses of the Anti-Staphylococcal Lysin, LSVT-1701, in Healthy Adult Subjects
Announcements Antimicrobial agents and chemotherapy. Date of publication 202203
Co-researcher Mary Beth Wire, Soo Youn Jun, In-Jin Jang, Seung-Hwan Lee, Jun Gi Hwang, David B Huang
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35007129/
Education / Career
Article Comparative Pharmacokinetics Between a Fixed-Dose Combination of Pitavastatin/Valsartan 4/160 mg and the Corresponding Individual Components Through a Partial Replicated Crossover Design in Healthy Male Subjects
Announcements Clinical pharmacology in drug development. Date of publication 202205
Co-researcher Joo Young Na, Eunsol Yang, Jae-Hoon Kim, In Sun Kwon, Eun-Heui Jin, Kyung-Sang Yu, Jinsook Kim, SeungHwan Lee, Jang Hee Hong
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34997835/
Education / Career
Article Evaluation of a blockchain-based dynamic consent platform (METORY) in a decentralized and multicenter clinical trial using virtual drugs
Announcements Clin Transl Sci Date of publication 202205
Co-researcher Ki Young Huh, Seol Ju Moon, Sang-Un Jeong, Min-Ji Kim, Wooseok Yang, Myeonggyu Jeong, Min-Gul Kim, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35157788/
Education / Career
Article Evaluation of food effects on the pharmacokinetics of Pelargonium sidoides and Coptis with each bioactive compound berberine and epicatechin after a single oral dose of an expectorant and antitussive agent UI026 in healthy subjects
Announcements Transl Clin Pharmacol Date of publication 202203
Co-researcher Yewon Park, WonTae Jung, Eunsol Yang, Kyu-Yeol Nam, Woo-Ri Bong, Jaehee Kim, Kyu Yeon Kim, SeungHwan Lee, Joo-Youn Cho, Jang-Hee Hong, JaeWoo Kim
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35419311/
Education / Career
Article Comparative pharmacokinetics between two tablets of tramadol 37.5 mg/acetaminophen 325 mg and one tablet of tramadol 75 mg/acetaminophen 650 mg for extended-release fixed-dose combination
Announcements Transl Clin Pharmacol Date of publication 202206
Co-researcher Hyun Chul Kim, Deok Yong Yoon, SeungHwan Lee, In-Jin Jang, Jang Hee Hong, JaeWoo Kim
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35800670/
Education / Career
Article Lessons from a multicenter clinical trial with an approved wearable electrocardiogram: issues and practical considerations
Announcements Transl Clin Pharmacol Date of publication 202206
Co-researcher Ki Young Huh, Sae Im Jeong, Hyounggyoon Yoo, Meihua Piao, Hyeongju Ryu, Heejin Kim, Young-Ran Yoon, Sook Jin Seong, SeungHwan Lee, Kyung Hwan Kim
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35800668/
Education / Career
Article Development of a Demand-Driven Blockchain-Based Dynamic Consent Platform Tailored for Clinical Trials
Announcements Front Med (Lausanne) Date of publication 202205
Co-researcher Ki Young Huh, Sang-Un Jeong, Seol Ju Moon, Min-Ji Kim, Wooseok Yang, Myeonggyu Jeong, Ildae Song, Yong-Geun Kwak, SeungHwan Lee, Min-Gul Kim
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/35646983/
Education / Career
Article Endogenous metabolic markers for predicting the activity of dihydropyrimidine dehydrogenase
Announcements Clin Transl Sci Date of publication 202205
Co-researcher Jihyun Kang, Andrew HyoungJin Kim, Inseung Jeon, Jaeseong Oh, In-Jin Jang, SeungHwan Lee, Joo-Youn Cho
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34863048/
Education / Career
Article Exploration for the effect of renal function and renal replacement therapy on pharmacokinetics of remdesivir and GS-441524 in patients with COVID-19: A limited case series
Announcements Clin Transl Sci Date of publication 202203
Co-researcher Pyoeng Gyun Choe, Sae Im Jeong, Chang Kyung Kang, Liju Yang, SeungHwan Lee, Joo-Youn Cho, Seung Seok Han, Dong Ki Kim, Sang Min Lee, Wan Beom Park, Myoung-Don Oh, Nam Joong Kim
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34761554/
Education / Career
Article Pharmacokinetics and safety of cenobamate, a novel antiseizure medication, in healthy Japanese, and an ethnic comparison with healthy non-Japanese
Announcements Clin Transl Sci Date of publication 202202
Co-researcher Eunsol Yang, Jung Sunwoo, Ki Young Huh, Yu Kyong Kim, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34670008/
Education / Career
Article Pharmacokinetics and safety of a novel influenza treatment (baloxavir marboxil) in Korean subjects compared with Japanese subjects
Announcements Clin Transl Sci Date of publication 202202
Co-researcher Yun Kim, Sangwon Lee, Yohan Kim, In-Jin Jang, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34664769/
Education / Career
Article Evaluation of safety and pharmacokinetics of bismuth-containing quadruple therapy with either vonoprazan or lansoprazole for Helicobacter pylori eradication
Announcements Br J Clin Pharmacol Date of publication 202201
Co-researcher Ki Young Huh, Hyewon Chung, Yu Kyong Kim, Seung Hwan Lee, Siddharth Bhatia, Yohei Takanami, Ryou Nakaya, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34080718/
Education / Career
Article Effect of meal timing on pharmacokinetics and pharmacodynamics of tegoprazan in healthy male volunteers
Announcements Clin Transl Sci Date of publication 202105
Co-researcher Deok Y Yoon, Jung Sunwoo, Naree Shin, Ah R Kim, Bongtae Kim, Geun S Song, In-Jin Jang, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33382926/
Education / Career
Article Comparative Pharmacokinetics/Pharmacodynamics of Fixed-Dose Combination of Esomeprazole and Calcium Carbonate (AD-206) to the Conventional Esomeprazole
Announcements Drug design, development and therapy. Date of publication 202112
Co-researcher Sungyeun Bae, Jihoon Kwon, Si-Beum Lee, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34992346/
Education / Career
Article Pharmacokinetic Interaction Among Ezetimibe, Rosuvastatin, and Telmisartan
Announcements Clin Pharmacol Drug Dev. Date of publication 202111
Co-researcher Ki Young Huh, Sang Won Lee, Si Beum Lee, Kyung Tae Kim, In-Jin Jang, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33647189/
Education / Career
Article Pharmacokinetics of Ginsenoside Compound K From a Compound K Fermentation Product, CK-30, and From Red Ginseng Extract in Healthy Korean Subjects
Announcements Clin Pharmacol Drug Dev. Date of publication 202111
Co-researcher Mu Seong Ban, Yun Kim, Sunyoung Lee, ByongYeul Han, Kyung-Sang Yu, In-Jin Jang, Hong Keun Chung, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33884767/
Education / Career
Article The necessary conduct: Exploratory multiregional clinical trials in East Asia
Announcements Clin Transl Sci Date of publication 202111
Co-researcher Inseung Jeon, Yu Kyong Kim, Ildae Song, Deok Yong Yoon, Ki Young Huh, Xuanyou Jin, Kyung-Sang Yu, SeungHwan Lee, Yuji Kumagai, In-Jin Jang
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34397152/
Education / Career
Article Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform
Announcements Transl Clin Pharmacol Date of publication 202109
Co-researcher Byungwook Kim, Deok Yong Yoon, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu, Joo-Youn Cho, Jaeseong Oh
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34621706/
Education / Career
Article Prediction of Drug-Drug Interaction Potential of Tegoprazan Using Physiologically Based Pharmacokinetic Modeling and Simulation
Announcements Pharmaceutics Date of publication 202109
Co-researcher Deok Yong Yoon, SeungHwan Lee, In-Jin Jang, Myeongjoong Kim, Heechan Lee, Seokuee Kim, Bongtae Kim, Geun Seog Song, Su-Jin Rhee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34575565/
Education / Career
Article Changes in the gut microbiome influence the hypoglycemic effect of metformin through the altered metabolism of branched-chain and nonessential amino acids
Announcements Diabetes Res Clin Pract Date of publication 202108
Co-researcher Yujin Lee, Andrew HyoungJin Kim, Eunwoo Kim, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Jae-Yong Chung, Joo-Youn Cho
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34329692/
Education / Career
Article Pharmacokinetic Equivalence of CT-P17 to High-Concentration (100 mg/mL) Reference Adalimumab: A Randomized Phase I Study in Healthy Subjects
Announcements Clinical and translational science. Date of publication 202107
Co-researcher Kyung-Sang Yu, In-Jin Jang, Hyeong-Seok Lim, Jang Hee Hong, Min-Gul Kim, Min Kyu Park, Doo-Yeoun Cho, Min Soo Park, Jae Yong Chung, Jong-Lyul Ghim, SeungHwan Lee, Seok Kyu Yoon, In Sun Kwon, Sang Joon Lee, Sung Hyun Kim, Yun Ju Bae, Jung Bin Cha, Daniel E Furst, Edward Keystone, Jonathan Kay
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33503313/
Education / Career
Article Pharmacokinetics, Tolerability and Pharmacogenetics of DA-8031 After Multiple Ascending Doses in Healthy Male Subjects
Announcements Drug Design, Development and Therapy Date of publication 202106
Co-researcher Sejung Hwang, Dae Young Lee, Joo-Youn Cho, Jae-Yong Chung, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/34103898/
Education / Career
Article Comparison of Pharmacokinetic, Pharmacodynamic and Tolerability Profiles of CKD-11101, Darbepoetin Alfa (NESP�) Biosimilar, to Those of NESP� After a Single Subcutaneous or Intravenous Administration to Healthy Subjects
Announcements Drug Des Devel Ther. Date of publication 202104
Co-researcher Inseung Jeon, Jaeseong Oh, Yu-Kyung Kwon, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33953543/
Education / Career
Article Pharmacokinetics and Safety of Extended-release Ranolazine in Korean and White Healthy Subjects
Announcements Clinical therapeutics. Date of publication 202103
Co-researcher Hyounggyoon Yoo, Sang Won Lee, Deok Yong Yoon, Seo Hyun Yoon, Joo-Youn Cho, Kyung-Sang Yu, In-Jin Jang, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33518355/
Education / Career
Article Pharmacokinetic comparison between tablet of varenicline tartrate and orally disintegrating film of varenicline salicylate in healthy subjects
Announcements Int J Clin Pharmacol Ther Date of publication 202106
Co-researcher Eunwoo Kim, Jun Gi Hwang, Su Jun Park, Ji Young Han, Young-Sim Choi, Se-Rin Park, Kyung-Sang Yu, Min Kyu Park, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33704052/
Education / Career
Article Pharmacokinetic comparison between a fixed-dose combination of fimasartan/amlodipine/ hydrochlorothiazide 60/10/25 mg and a corresponding loose combination of fimasartan/amlodipine 60/25 mg and hydrochlorothiazide 25 mg in healthy subjects
Announcements Transl Clin Pharmacol Date of publication 202103
Co-researcher Jihyun Jung, Soyoung Lee, Jaeseong Oh, SeungHwan Lee, In-Jin Jang, Donghwan Lee, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33855001/
Education / Career
Article Population pharmacokinetic model development and its relationship with adverse events of oxcarbazepine in adult patients with epilepsy
Announcements Sci Rep. Date of publication 202103
Co-researcher Yoonhyuk Jang, Seonghae Yoon, Tae-Joon Kim, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Kon Chu, Sang Kun Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33737678/
Education / Career
Article Comparative pharmacokinetics between tenofovir disoproxil phosphate and tenofovir disoproxil fumarate in healthy subjects
Announcements Transl Clin Pharmacol. Date of publication 202103
Co-researcher Sangmi Lee, Eunwoo Kim, Seol Ju Moon, Jina Jung, SeungHwan Lee, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33855000/
Education / Career
Article Pharmacokinetic and Pharmacodynamic Comparison of Two Formulations of a Fixed-Dose Combination of Gemigliptin/Rosuvastatin 50/20 mg: A Randomized, Open-Label, Single-Dose, Two-Way Crossover Study
Announcements Drug Des Devel Ther Date of publication 202102
Co-researcher Eunsol Yang, Hyounggyoon Yoo, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33628012/
Education / Career
Article Comparison of the Pharmacokinetics of a Fixed-Dose Combination of Rosuvastatin/Metformin Sustained-Release (10/1000 Mg) and Separate Tablets in Healthy Male Subjects
Announcements Clinical pharmacology in drug development Date of publication 202102
Co-researcher Ki Young Huh, Eunwoo Kim, Heechan Lee, Inseung Jeon, Hearan Suh, Jongsun Lee, Yunhee Lee, Kyung-Sang Yu, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32579298/
Education / Career
Article Effects of perampanel on cognition and quantitative electroencephalography in patients with epilepsy
Announcements Epilepsy Behav Date of publication 202102
Co-researcher Seon-Jae Ahn, Tae-Joon Kim, Kwang Su Cha , Jin-Sun Jun , Jung-Ick Byun , Yong-Won Shin , Jun-Sang Sunwoo , SeungHwan Lee , Kyung-Sang Yu , In-Jin Jang , Kon Chu , Sang Kun Lee , Ki-Young Jung
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33328106/
Education / Career
Article Tolerability of lacosamide rapid dose titration: A randomized, multicenter, prospective, open-label study
Announcements Epilepsy Behav Date of publication 202102
Co-researcher Yong-Won Shin, Jangsup Moon, Yong Won Cho, Dong Wook Kim, Sang Bin Hong, Do-Yong Kim, Hyeyeon Chang, Seo Hyun Yoon, Kyung-Sang Yu, In-Jin Jang, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Ki-Young Jung , Manho Kim, Kon Chu, SeungHwan Lee, Sang Kun Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33342710/
Education / Career
Article Urinary metabolic markers reflect on hepatic, not intestinal, CYP3A activity in healthy subjects
Announcements Drug Metab Pharmacokinet Date of publication 202102
Co-researcher Soyoung Lee, Yujin Lee, Andrew HyoungJin Kim, Sumin Yoon, Jieon Lee, Sang Chun Ji, Seo Hyun Yoon, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Joo-Youn Cho
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33348239/
Education / Career
Article The utility of CYP3A activity endogenous markers for evaluating drug-drug interaction between sildenafil and CYP3A inhibitors in healthy subjects
Announcements Drug Metab Pharmacokinet Date of publication 202102
Co-researcher Soyoung Lee, Andrew HyoungJin Kim, Sumin Yoon, Jieon Lee, Yujin Lee, Sang Chun Ji, Seo Hyun Yoon, SeungHwan Lee, Kyung-Sang Yu , In-Jin Jang , Joo-Youn Cho
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33348240/
Education / Career
Article Editorial: acid suppression with potassium-competitive acid blockers-dismissing genotype concerns. Authors' reply
Announcements Aliment Pharmacol Ther Date of publication 202101
Co-researcher Jun Gi Hwang, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33333601/
Education / Career
Article Editorial: pharmacodynamics of potassium-competitive acid blockers: comparing apples with apples - and with oranges. Authors' reply
Announcements Aliment Pharmacol Ther Date of publication 202101
Co-researcher Jung Sunwoo, Ji Yeon Nam, Bongtae Kim, Geun Seog Song, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33333599/
Education / Career
Article Pharmacodynamics and pharmacokinetics of DWP14012 (fexuprazan) in healthy subjects with different ethnicities
Announcements Aliment Pharmacol Ther Date of publication 202012
Co-researcher Jun Gi Hwang, Inseung Jeon, Sun Ae Park, Areum Lee, Kyung-Sang Yu, In-Jin Jang, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33111337/
Education / Career
Article Pharmacodynamics of tegoprazan and revaprazan after single and multiple oral doses in healthy subjects
Announcements Aliment Pharmacol Ther Date of publication 202012
Co-researcher Jung Sunwoo, Sang Chun Ji, Jaeseong Oh, Mu Seong Ban, Ji Yeon Nam, Bongtae Kim, Geun Seog Song, Kyung-Sang Yu, In-Jin Jang , SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33131095/
Education / Career
Article Oral absorption of voriconazole is affected by SLCO2B1 c.*396T>C genetic polymorphism in CYP2C19 poor metabolizers
Announcements Pharmacogenomics J Date of publication 202012
Co-researcher Sang Won Lee, Jaeseong Oh, Andrew HyoungJin Kim , Sang Chun Ji, Sang-In Park , Seo Hyun Yoon, Jae-Young Chung, Kyung-Sang Yu, In-Jin Jang, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32461666/
Education / Career
Article Pharmacogenomic information from CPIC and DPWG guidelines and its application on drug labels
Announcements Transl Clin Pharmacol Date of publication 202012
Co-researcher Deok Yong Yoon , Soyoung Lee , Mu Seong Ban , In-Jin Jang, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33425802/
Education / Career
Article Effect of Meal Timing on Pharmacokinetics and Pharmacodynamics of Tegoprazan in Healthy Male volunteers
Announcements Clin Transl Sci Date of publication 202012
Co-researcher Deok Yong Yoon , Jung Sunwoo, Naree Shin , Ah Rong Kim , Bong Tae Kim , Geun Seog Song , In-Jin Jang , SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33382926/
Education / Career
Article Electronic medical records-based comparison of glycemic control efficacy between sulfonylureas and dipeptidyl peptidase-4 inhibitors added on to metformin monotherapy in patients with type 2 diabetes
Announcements TCP Date of publication 202012
Co-researcher Suhrin Lee , SeungHwan Lee , In-Jin Jang , Kyung-Sang Yu , and Su-jin Rhee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33425803/
Education / Career
Article Pharmacokinetic/Pharmacodynamic Interactions Between Evogliptin and Glimepiride in Healthy Male Subjects
Announcements Drug Des Devel The Date of publication 202011
Co-researcher Hyounggyoon Yoo, Yun Kim, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33262578/
Education / Career
Article Population Pharmacokinetic Analysis of Amikacin for Optimal Pharmacotherapy in Korean Patients with Nontuberculous Mycobacterial Pulmonary Disease
Announcements Antibiotics. Date of publication 202011
Co-researcher Xuanyou Jin, Jaeseong Oh, Joo-Youn Cho, SeungHwan Lee, Su-Jin Rhee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33172135/
Education / Career
Article Pharmacokinetic/Pharmacodynamic Interaction Between Evogliptin and Pioglitazone in Healthy Male Subjects
Announcements Drug Des Devel The Date of publication 202010
Co-researcher Inyoung Hwang, Yun Kim, Hyounggyoon Yoo, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/33122892/
Education / Career
Article Pharmacokinetics and Tolerability of LC28-0126, a Novel Necrosis Inhibitor, After Multiple Ascending Doses: A Phase I Randomized, Double-blind, Placebo-controlled Study in Healthy Male Subjects
Announcements Clinical therapeutics. Date of publication 202010
Co-researcher Eunwoo Kim , Inyoung Hwang, SeungHwan Lee, Jaeseong Oh, Hyewon Chung, Myungwon Jin, Soon Ha Kim, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32980184/
Education / Career
Article Impact of vancomycin-induced changes in the intestinal microbiota on the pharmacokinetics of simvastatin.
Announcements Clin Transl Sci Date of publication 202007
Co-researcher Jung Sunwoo Sang Chun Ji Andrew HyoungJin Kim Kyung‐Sang Yu Joo‐Youn Cho In‐Jin Jang SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32058642/
Education / Career
Article Usefulness of saliva for perampanel therapeutic drug monitoring. in Epilepsia has the following publication status
Announcements Epilepsia Date of publication 202006
Co-researcher Do-Yong Kim, Jangsup Moon, Yong-Won Shin, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Ki-Young Jung, Manho Kim, SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, KaHeon Song, Kon Chu, Sangkun Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32378757/
Education / Career
Article Comparison of the Pharmacokinetics of Highly Variable Drugs in Healthy Subjects Using a Partial Replicated Crossover Study: A Fixed-Dose Combination of Fimasartan 120 mg and Atorvastatin 40 mg versus Separate Tablets.
Announcements Drug Des Devel The Date of publication 202005
Co-researcher Jun Gi Hwang, Kyung-Sang Yu, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32546962/
Education / Career
Article Regulatory aspects of xenotransplantation in Korea
Announcements Xenotransplantation Date of publication 202005
Co-researcher Ivo Kwon, Chung-Gyu Park, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32420655/
Education / Career
Article Comparison of In Vivo Pharmacokinetics and Pharmacodynamics of Vancomycin Products Available in Korea
Announcements Yonsei Med J Date of publication 202004
Co-researcher Hee Kyung Kim, Su Mi Choi, Gaeun Kang, Kyung Hwa Park, Dong Gun Lee, Wan Beom Park, Su Jin Rhee, SeungHwan Lee, Sook In Jung , Hee Chang Jang
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32233172/
Education / Career
Article Pharmacokinetics and Pharmacodynamics of a Fixed-Dose Combination of gemigliptin/metformin Sustained Release 25/500 Mg Compared to the Loose Combination in Healthy Male Subjects
Announcements Translational and clinical pharmacology Date of publication 202003
Co-researcher Xuanyou Jin, Eunwoo Kim, Ki Young Huh, Inyoung Hwang, Joo-Youn Cho, Kyung-Sang Yu, SeungHwan Lee
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32274380/
Education / Career
Article Possibility of pharmacokinetic drug interaction between a DPP-4 inhibitor and a SGLT2 inhibitor
Announcements Transl Clin Pharmacol Date of publication 202003
Co-researcher Namyi Gu, Sang-In Park, Hyewon Chung, Xuanyou Jin, SeungHwan Lee, Tae-Eun Kim
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/32274378/
Education / Career
Article Quantitative prediction of hepatic CYP3A activity using endogenous markers in healthy subjects after administration of CYP3A inhibitors or inducers.
Announcements Drug metabolism and pharmacokinetics Date of publication 201908
Co-researcher Jieon Lee, Seo Hyun Yoon, Sojeong Yi, Andrew HyoungJin Kim, Bora Kim,SeungHwan Lee, Kyung-Sang Yu, In-Jin Jang, Joo-Youn Cho
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/31088714/
Education / Career
Article Population Pharmacokinetic Study of Prophylactic Fluconazole in Preterm Infants for Prevention of Invasive Candidiasis
Announcements Antimicrobial agents and chemotherapy Date of publication 201905
Co-researcher Kim YK, Lee J, Oh J, Rhee SJ, Shin SH, Yoon SH, Lee S, Kim HS, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30910892/
Education / Career
Article Pharmacokinetic comparison of gemigliptin 50 mg and metformin 500 mg as a fixed-dose combination and loose combination

Announcements International journal of clinical pharmacology and therapeutics Date of publication 201902
Co-researcher Lee SW, Park SI, Lee S, Chung JY, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30574864/
Education / Career
Article Ursodeoxycholic acid exerts hepatoprotective effects by regulating amino acid, flavonoid, and fatty acid metabolic pathways
Announcements Metabolomics Society Date of publication 201902
Co-researcher Da Jung Kim , Hyewon Chung, Sang Chun Ji, SeungHwan Lee,Kyung‑Sang Yu, In‑Jin Jang, Joo‑Youn Cho
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30830474/
Education / Career
Article A Personalized CYP2C19 Phenotype-Guided Dosing Regimen of Voriconazole Using a Population Pharmacokinetic Analysis
Announcements Journal of clinical medicine Date of publication 201902
Co-researcher Kim Y, Rhee SJ, Park WB, Yu KS, Jang IJ, Lee S
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30744151/
Education / Career
Article Effect of food on the pharmacokinetics of YH4808, a potassium-competitive acid blocker, after single- and multiple-oral dosing in healthy subjects.
Announcements EUR J CLIN PHARMACOL Date of publication 201810
Co-researcher Kim E, Kim A, Yi S, Kim YK, Jang SB, Byun HM, Yoon SH, Cho JY, Jang IJ, Yu KS, Lee S
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29907887/
Education / Career
Article Assessment of Hepatic Cytochrome P450 3A Activity Using Metabolic Markers in Patients with Renal Impairment
Announcements Journal of Korean medical science Date of publication 201810
Co-researcher Kim AH1, Yoon S1, Lee Y1, Lee J1, Bae E2, Lee H3, Kim DK3, Lee S1, Yu KS1, Jang IJ1, Cho JY1.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30595680/
Education / Career
Article Ursodeoxycholic acid improves liver function via phenylalanine/ tyrosine pathway and microbiome remodelling in patients with liver dysfunction
Announcements Scientific reports Date of publication 201808
Co-researcher Kim DJ, Yoon S, Ji SC, Yang J, Kim YK, Lee S, Yu KS, Jang IJ, Chung JY, Cho JY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30089798/
Education / Career
Article Pharmacokinetic interaction between fimasartan and atorvastatin in healthy male volunteers
Announcements Drug Des Devel Ther Date of publication 201807
Co-researcher Yewon Choi, SeungHwan Lee, In-Jin Jang, Kyung-Sang Yu
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/30087555/
Education / Career
Article Safety, tolerability, pharmacodynamics and pharmacokinetics of DWP14012, a novel potassium-competitive acid blocker, in healthy male subjects
Announcements Aliment. Pharmacol. Ther Date of publication 201807
Co-researcher Sunwoo J, Oh J, Moon SJ, Ji SC, Lee SH, Yu KS, Kim HS, Lee A, Jang IJ
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29863280/
Education / Career
Article Evaluation of the effects of food on levodropropizine controlled-release tablet and its pharmacokinetic profile in comparison to that of immediate-release tablet.
Announcements Drug Des Devel Ther Date of publication 201805
Co-researcher Lee S, Nam KY, Oh J, Lee S, Cho SM, Choi YW, Cho JY, Lee BJ, Hong JH
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29872264/
Education / Career
Article Identification of ω- or (ω-1)-Hydroxylated Medium-Chain Acylcarnitines as Novel Urinary Biomarkers for CYP3A Activity.
Announcements Clin Pharmacol Ther Date of publication 201805
Co-researcher Kim B, Lee J, Shin KH, Lee S, Yu KS, Jang IJ, Cho JY.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28877336/
Education / Career
Article A post hoc analysis of intra-subject coefficients of variation in pharmacokinetic measures to calculate optimal sample sizes for bioequivalence studies
Announcements Transl Clin Pharmacol Date of publication 201803
Co-researcher Inbum Chung, Jaeseong Oh, SeungHwan Lee, In-Jin Jang, Youngjo Lee, Jae-Yong Chung
Education / Career
Article Assessment of Appropriateness of an Initial Dosing Regimen of Vancomycin and Development of a New Dosing Nomogram.
Announcements Basic Clin Pharmacol Toxicol Date of publication 201802
Co-researcher Yoon S, Park KR, Lee S, Song SH, Park WB, Jang IJ, Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28834212/
Education / Career
Article Single-Dose Comparative Pharmacokinetics of Two Formulations of Lenalidomide 25 mg in Healthy Subjects: A Randomized Crossover Study.
Announcements Advances in therapy Date of publication 201802
Co-researcher Lee S, Hwang JG, Park SY, Lim HJ, Lee SW, Seo MH, Kim J, Hong JH
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29411269/
Education / Career
Article Pharmacokinetics and tolerability of eletriptan hydrobromide in healthy Korean subjects.
Announcements Drug Des Devel Ther Date of publication 201802
Co-researcher Kim YK, Shin KH, Alderman J, Yu KS, Jang IJ, Lee S.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29497279/
Education / Career
Article Safety, Tolerability, and Pharmacokinetic Characteristics of a Novel Nonopioid Analgesic, VVZ-149 Injections in Healthy Volunteers: A First-in-Class, First-in-Human Study.
Announcements J Clin Pharmacol Date of publication 201801
Co-researcher Oh J, Lee S, Kim A, Yoon J, Jang K, Lee DH, Cho S, Lee SR, Yu KS, Chung JY.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28815639/
Education / Career
Article Pharmacokinetics and tolerability of MB12066, a beta-lapachone derivative targeting NAD(P)H: quinone oxidoreductase 1: two independent, double-blind, placebo-controlled, combined single and multiple ascending dose first-in-human clinical trials.
Announcements Drug Des Devel Ther Date of publication 201711
Co-researcher Kim S,Lee S,Cho JY,Yoon SH,Jang IJ,Yu KS,
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29158665/
Education / Career
Article A comparative pharmacokinetic and tolerability analysis of the novel orotic acid salt form of tenofovir disoproxil and the fumaric acid salt form in healthy subjects.
Announcements Drug Des Devel Ther Date of publication 201711
Co-researcher Kim YK, Choi MJ, Oh TY, Yu KS, Lee S
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29158663/
Education / Career
Article Comparable pharmacokinetics and pharmacodynamics of two epoetin alfa formulations Eporon and Eprex following a single subcutaneous administration in healthy male volunteers.
Announcements Drug Des Devel Ther Date of publication 201710
Co-researcher Yoon S,Rhee SJ,Heo SJ,Oh TY,Yoon SH,Cho JY,Lee S,Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/29138535/
Education / Career
Article Pharmacokinetics, Safety, and Tolerability of Tedizolid Phosphate After Single-dose Administration in Healthy Korean Male Subjects.
Announcements Clin Ther Date of publication 201709
Co-researcher Kim Y, Kim A, Lee S, Choi SH, Lee DY, Song JS, Lee H, Jang IJ, Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28865799/
Education / Career
Article LBEC0101, A Proposed Etanercept Biosimilar: Pharmacokinetics, Immunogenicity, and Tolerability Profiles Compared with a Reference Biologic Product in Healthy Male Subjects.
Announcements BioDrugs Date of publication 201708
Co-researcher Lee H,Chung H,Lee S,Lee H,Yang SM,Yoon SH,Cho JY,Jang IJ,Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28551775/
Education / Career
Article Distribution of Exogenous and Endogenous CYP3A Markers and Related Factors in Healthy Males and Females.
Announcements AAPS J Date of publication 201707
Co-researcher Lee J,Kim AH,Yi S,Lee S,Yoon SH,Yu KS,Jang IJ,Cho JY
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28523515/
Education / Career
Article Pharmacokinetic comparison using two tablets of an evogliptin/metformin XR 2.5/500 mg fixed dose combination vs. 1 tablet each of evogliptin 5 mg and metformin XR 1,000 mg
.
Announcements Int J Clin Pharmacol Ther Date of publication 201706
Co-researcher Yoon S,Rhee SJ,Park SI,Yoon SH,Cho JY,Jang IJ,Lee S,Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28406090/
Education / Career
Article Pharmacokinetics and Safety of a Single Dose of the Novel Necrosis Inhibitor LC28-0126 in Healthy Male Subjects
Announcements Br J Clin Pharmacol Date of publication 201706
Co-researcher Kim S,Chung H,Lee SH,Cho SH,Cho HJ,Kim SH,Jang IJ,Yu KS.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28002882/
Education / Career
Article A Significant Influence of Metronidazole on Busulfan Pharmacokinetics: A Case Report of Therapeutic Drug Monitoring.
Announcements Ther Drug Monit Date of publication 201706
Co-researcher Chung H,Yu KS,Hong KT,Choi JY,Hong CR,Kang HJ,Park KD,Shin HY,Lee S.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28328762/
Education / Career
Article A randomized, double-blind, single-dose, two-arm, parallel study comparing pharmacokinetics, immunogenicity and tolerability of branded adalimumab and its biosimilar LBAL in healthy male volunteers.
Announcements Expert Opin Investig Drugs Date of publication 201705
Co-researcher Park KR,Chung H,Yang SM,Lee S,Yoon SH,Cho JY,Jang IJ,Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28290731/
Education / Career
Article Pharmacokinetics and tolerability of DA-8031, a novel selective serotonin reuptake inhibitor for premature ejaculation in healthy male subjects.
Announcements Drug Des Devel Ther Date of publication 201705
Co-researcher Shin D,Lee S,Yi S,Yoon SH,Cho JY,Bahng MY,Jang IJ,Yu KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28331291/
Education / Career
Article Population pharmacokinetics and dose-response relationship of levetiracetam in adult patients with epilepsy.
Announcements Epilepsy Res. Date of publication 201705
Co-researcher Rhee SJ,Shin JW,Lee S,Moon J,Kim TJ,Jung KY,Park KI,Lee ST,Jung KH,Yu KS,Jang IJ,Chu K,Lee SK.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28279893/
Education / Career
Article Exploration of Biomarkers for Amoxicillin/Clavulanate-Induced Liver Injury: Multi-Omics Approaches.
Announcements Clin Transl Sci Date of publication 201705
Co-researcher Lee J,Ji SC,Kim B,Yi S,Shin KH,Cho JY,Lim KS,Lee SH,Yoon SH,Chung JY,Yu KS,Park HS,Kim SH,Jang IJ
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/27785887/
Education / Career
Article Effects of dexamethasone coadministered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers
Announcements Drug Design, Development and Therapy Date of publication 201705
Co-researcher Jang K, Kim M, Oh J, Lee S, Cho J, Yu K, Choi T, Lee S, Lim K,
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28331290/
Education / Career
Article A first-in-human, double-blind, placebo-controlled, randomized, dose escalation study of DWP05195, a novel TRPV1 antagonist, in healthy volunteers.
Announcements Drug Des Devel Ther.� Date of publication 201704
Co-researcher Lee J,Kim BH,Yu KS,Kim HS,Kim JD,Cho JY,Lee S,Gu N.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28479852/
Education / Career
Article The novel carboxylesterase 1 variant c.662A>G may decrease the bioactivation of oseltamivir in humans.
Announcements PLoS ONE Date of publication 201704
Co-researcher Oh J, Lee S, Lee H, Cho JY, Yoon SH, Jang IJ, Yu KS, Lim KS
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28437488/
Education / Career
Article Changes in Cardiac Function After a Single Intravenous Administration of CKD-712 in Healthy Male Volunteers.
Announcements Clin Drug Investig Date of publication 201704
Co-researcher Park SI,Kim J,Yu KS,Jang IJ,Lee S.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28160190/
Education / Career
Article Bioequivalence of two formulations of pregabalin 150-mg capsules under fasting conditions in healthy male subjects
.
Announcements Int J Clin Pharmacol Ther Date of publication 201702
Co-researcher Lee HA,Lee S,Yim SV,Kim BH.
Pubmed URL https://www.ncbi.nlm.nih.gov/pubmed/28025964/

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