SEOUL NATIONAL UNIVERSITY HOSPITAL

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尹泓晳

Department

Department of Genomic Medicine

Center for Precision Medicine

Specialty

Genomic Medicine , Precision Medicine , Genetic analysis
Precision Medicine

网上预约

Education / Career

Education / Career
Article	Prediction of metabolites associated with somatic mutations in cancers by using genome-scale metabolic models and mutation data
Announcements	Genome Biol	Date of publication	2024-03
Co-researcher	Lee G, Lee SM, Lee S, Jeong CW, Song H, Lee SY, Yun H, Koh Y, Kim HU
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/38468344/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/38468344/

Education / Career
Article	Multiple Primary Cancers With Hematologic Malignancies and Germline Predisposition: A Case Series
Announcements	Ann Lab Med	Date of publication	2024-03
Co-researcher	Yun J, Lee DS, Lee S, Yun H
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/38449380/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/38449380/

Education / Career
Article	Methylation-based Subclassifications of Embryonal Tumor with Multilayered Rosettes in Not Just Pediatric Brains
Announcements	Exp Neurobiol	Date of publication	2023-08
Co-researcher	Kim EE, Lee K, Phi JH, Kim MS, Kang HJ, Yun H, Park SH
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/37927133/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/37927133/

Education / Career
Article	Distinct mutational pattern of T-cell large granular lymphocyte leukemia combined with pure red cell aplasia: low mutational burden of STAT3
Announcements	Sci Rep	Date of publication	2023-05
Co-researcher	Park S, Yun J, Choi SY, Jeong D, Gu JY, Lee JS, Seong MW, Chang YH, Yun H, Kim HK
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/37142644/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/37142644/

Education / Career
Article	Genomic profiles of IDH-mutant gliomas: MYCN-amplified IDH-mutant astrocytoma had the worst prognosis
Announcements	Sci Rep	Date of publication	2023-04
Co-researcher	Lee K, Kim SI, Kim EE, Shim YM, Won JK, Park CK, Choi SH, Yun H, Lee H, Park SH
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/37185778/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/37185778/

Education / Career
Article	Expanding the Clinicopathologic Spectrum of YAP1::MAML2-Rearranged Thymic Neoplasm
Announcements	Mod Pathol	Date of publication	2023-02
Co-researcher	Kim EE, Suh YY, Lee SW, Bae JM, Lee K, Lee S, Yun H, Jung KC, Koh J
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/36853792/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/36853792/

Education / Career
Article	Analysis of clinical and genomic profiles of therapy-related myeloid neoplasm in Korea
Announcements	Hum Genomics	Date of publication	2023-02
Co-researcher	Yun J, Song H, Kim SM, Kim S, Kwon SR, Lee YE, Jeong D, Park JH, Kwon S, Yun H, Lee DS
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/36814285/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/36814285/

Education / Career
Article	ITDetect: a method to detect internal tandem duplication of FMS-like tyrosine kinase (FLT3) from next-generation sequencing data with high sensitivity and clinical application
Announcements	BMC Bioinformatics	Date of publication	2023-02
Co-researcher	Lee S, Sun CH, Jang H, Kim D, Yoon SS, Koh Y, Na SC, Cho SI, Kim MJ, Seong MW, Byun JM, Yun H
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/36823555/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/36823555/

Education / Career
Article	Mitigating the BFL1-mediated antiapoptotic pathway in diffuse large B cell lymphoma by inhibiting HDACs
Announcements	Leuk Lymphoma	Date of publication	2023-01
Co-researcher	Park E, Lee C, Park J, Liu J, Hong J, Shin DY, Byun JM, Yun H, Koh Y, Yoon SS
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/36331521/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/36331521/

Education / Career
Article	Transcriptional signatures of the BCL2 family for individualized acute myeloid leukaemia treatment
Announcements	Genome Med	Date of publication	2022-09
Co-researcher	Lee C, Lee S, Park E, Hong J, Shin DY, Byun JM, Yun H, Koh Y, Yoon SS
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/36171613/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/36171613/

Education / Career
Article	Pediatric-Type Indolent B-Cell Lymphomas With Overlapping Clinical, Pathologic, and Genetic Features
Announcements	Am J Surg Pathol	Date of publication	2022-08
Co-researcher	Lim S, Lim KY, Koh J, Bae JM, Yun H, Lee C, Kim YA, Paik JH, Jeon YK
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/35834399/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/35834399/

Education / Career
Article	The telomere maintenance mechanism spectrum and its dynamics in gliomas
Announcements	Genome Med	Date of publication	2022-08
Co-researcher	Kim S, Chowdhury T, Yu HJ, Kahng JY, Lee CE, Choi SA, Kim KM, Kang H, Lee JH, Lee ST, Won JK, Kim KH, Kim MS, Lee JY, Kim JW, Kim YH, Kim TM, Choi SH, Phi JH, Shin YK, Ku JL, Lee S, Yun H, Lee H, Kim D, Kim K, Hur JK, Park SH, Kim SK, Park CK
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/35953846/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/35953846/

Education / Career
Article	Clinicopathologic and Genetic Features of Primary T-cell Lymphomas of the Central Nervous System: An Analysis of 11 Cases Using Targeted Gene Sequencing
Announcements	Am J Surg Pathol	Date of publication	2022-04
Co-researcher	Yim J, Koh J, Kim S, Song SG, Bae JM, Yun H, Sung JY, Kim TM, Park SH, Jeon YK
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/34980830/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/34980830/

Education / Career
Article	Consistent count region-copy number variation (CCR-CNV): an expandable and robust tool for clinical diagnosis of copy number variation at the exon level using next-generation sequencing data
Announcements	Genet Med	Date of publication	2022-03
Co-researcher	Kim MJ, Lee S, Yun H, Cho SI, Kim B, Lee JS, Chae JH, Sun C, Park SS, Seong MW
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/34906491/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/34906491/

Education / Career
Article	An unusual case of microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR) diffuse large B-cell lymphoma revealed by targeted gene sequencing
Announcements	J Pathol Transl Med	Date of publication	2022-03
Co-researcher	Han B, Kim S, Koh J, Bae JM, Yun H, Jeon YK
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/34775735/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/34775735/

Education / Career
Article	Genetic profile of primary plasma cell leukemia in Korea: comparison with plasma cell myeloma. Leuk Lymphoma
Announcements	Leuk Lymphoma	Date of publication	2022-02
Co-researcher	Lee Y, Yun J, Jeong D, Ryu S, Kwon SR, Yun H, Kim SM, Park JH, Lee DS
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/34592901/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/34592901/

Education / Career
Article	Sporadic and Lynch syndrome-associated mismatch repair-deficient brain tumors
Announcements	Lab Invest	Date of publication	2022-02
Co-researcher	Kim H, Lim KY, Park JW, Kang J, Won JK, Lee K, Shim Y, Park CK, Kim SK, Choi SH, Kim TM, Yun H, Park SH
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/34848827/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/34848827/

Education / Career
Article	Recommendations for the Use of Next-Generation Sequencing and the Molecular Tumor Board for Patients with Advanced Cancer: A Report from KSMO and KCSG Precision Medicine Networking Group
Announcements	Cancer Res Treat	Date of publication	2022-01
Co-researcher	Yoon S, Kim M, Hong YS, Kim HS, Kim ST, Kim J, Yun H, Yoo C, Ahn HK, Kim HS, Lee IH, Kim IH, Park I, Jeong JH, Cheon J, Kim JW, Yun J, Lim SM, Cha Y, Jang SJ, Zang DY, Kim TW, Kang JH, Kim JH
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/34902959/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/34902959/

Education / Career
Article	ZFTA-YAP1 fusion-positive ependymoma can occur in the spinal cord: Letter to the editor
Announcements	Brain Pathol	Date of publication	2022-01
Co-researcher	Lim KY, Lee KH, Phi JH, Yun H, Won JK, Choi SH, Park SH
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/34506076/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/34506076/

Education / Career
Article	Molecular subtyping of ependymoma and prognostic impact of Ki-67
Announcements	Brain Tumor Pathol	Date of publication	2022-01
Co-researcher	Lim KY, Lee K, Shim Y, Park JW, Kim H, Kang J, Won JK, Kim SK, Phi JH, Park CK, Chung CK, Yun H, Park SH
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/34812989/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/34812989/

Education / Career
Article	Revisiting vimentin: a negative surrogate marker of molecularly defined oligodendroglioma in adult type diffuse glioma
Announcements	Brain Tumor Pathol	Date of publication	2021-10
Co-researcher	Kim SI, Lee K, Bae J, Lee S, Yun H, Park CK, Choi SH, Maquiling CA, Park SH, Won JK
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/34338912/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/34338912/

Education / Career
Article	Clinical and Genomic Characteristics of Adult Diffuse Midline Glioma
Announcements	Cancer Res Treat	Date of publication	2021-04
Co-researcher	26. Park C, Kim TM, Bae JM, Yun H, Kim JW, Choi SH, Lee ST, Lee JH, Park SH, Park CK
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/33171023/
ETC URL	https://pubmed.ncbi.nlm.nih.gov/33171023/

Education / Career
Article	Proper Read Filtering Method to Adequately Analyze Whole-Transcriptome Sequencing and RNA Based Immune Repertoire Sequencing Data for Tumor Milieu Research
Announcements	Cancers (Basel)	Date of publication	2020/12
Co-researcher	Lee S, Song S, Yoon SS, Koh Y, Yun H
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/33317041/

Education / Career
Article	Clinical and Genomic Characteristics of Adult Diffuse Midline Glioma
Announcements	Cancer Res Treat	Date of publication	2020/09
Co-researcher	Park C, Kim TM, Bae JM, Yun H, Kim JW, Choi SH, Lee ST, Lee JH, Park SH, Park CK
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/33171023/

Education / Career
Article	MED-TMA: A clinical decision support tool for differential diagnosis of TMA with enhanced accuracy using an ensemble method
Announcements	Thromb Res	Date of publication	2020/09
Co-researcher	Yoon J, Lee S, Sun CH, Kim D, Kim I, Yoon SS, Oh D, Yun H, Koh Y
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/32622194/

Education / Career
Article	Liquid biopsy-based tumor profiling for metastatic colorectal cancer patients with ultra-deep targeted sequencing
Announcements	PLoS One	Date of publication	2020/05
Co-researcher	Kang JK, Heo S, Kim HP, Song SH, Yun H, Han SW, Kang GH, Bang D, Kim TY
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/32379795/

Education / Career
Article	NPM1 as a potential therapeutic target for atypical teratoid/rhabdoid tumors
Announcements	BMC Cancer	Date of publication	2019/08
Co-researcher	Phi JH, Sun CH, Lee SH, Lee S, Park I, Choi SA, Park SH, Lee JY, Wang KC, Kim SK, Yun H, Park CK
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/31462227/

Education / Career
Article	RTK-RAS pathway mutation is enriched in myeloid sarcoma
Announcements	Blood Cancer J	Date of publication	2018/05
Co-researcher	Choi M, Jeon YK, Sun CH, Yun HS, Hong J, Shin DY, Kim I, Yoon SS, Koh Y
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/29789584/

Education / Career
Article	Genetic Characteristics of Polycythemia Vera and Essential Thrombocythemia in Korean Patients
Announcements	J Clin Lab Anal	Date of publication	2016/11
Co-researcher	Yoo EH, Park KJ, Won HH, Park JH, Park JH, Lee ST, Kim HJ, Bang SM, Chi HS, Jung CW, Kim SH, Yun H, Sun CH, Park I, Lee S, Lee C, Merriman B, Luo R, Tan EH, Park KJ, Yoo NK, Kang JJ, Kim J
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/27132877/

Education / Career
Article	A scientific treatment approach for acute mast cell leukemia: using a strategy based on next-generation sequencing data
Announcements	Blood Res	Date of publication	2016/03
Co-researcher	Youk J, Koh Y, Kim JW, Kim DY, Park H, Jung WJ, Ahn KS, Yun H, Park I, Sun CH, Lee S, Yoon SS
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/27104187/

Education / Career
Article	Integrated genomic analyses identify frequent gene fusion events and VHL inactivation in gastrointestinal stromal tumors
Announcements	Oncotarget	Date of publication	2016/02
Co-researcher	Kang G, Yun H, Sun CH, Park I, Lee S, Kwon J, Do I, Hong ME, Van Vrancken M, Lee J, Park JO, Cho J, Kim KM, Sohn TS
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/25987131/

Education / Career
Article	Genomic dynamics associated with malignant transformation in IDH1 mutated gliomas
Announcements	Oncotarget	Date of publication	2015/12
Co-researcher	Park CK, Park I, Lee S, Sun CH, Koh Y, Park SH, Kim JE, Yun H, Lee SH
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/26524630/

Education / Career
Article	Detection of a Distinctive Genomic Signature in Rhabdoid Glioblastoma, A Rare Disease Entity Identified by Whole Exome Sequencing and Whole Transcriptome Sequencing
Announcements	Transl Oncol	Date of publication	2015/08
Co-researcher	Koh Y, Park I, Sun CH, Lee S, Yun H, Park CK, Park SH, Park JK, Lee SH
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/26310374/

Education / Career
Article	Revising a Personal Genome by Comparing and Combining Data from Two Different Sequencing Platforms
Announcements	PLoS One	Date of publication	2013/04
Co-researcher	Kim D, Kim WY, Lee SY, Lee SY, Yun H, Shin SY, Lee J, Hong Y, Won Y, Kim SJ, Lee YS, Ahn SM
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/23593254/

Education / Career
Article	Genome-wide identification of the subcellular localization of the Escherichia coli B proteome using experimental and computational methods
Announcements	Proteomics	Date of publication	2011/04
Co-researcher	Han MJ, Yun H, Lee JW, Lee YH, Lee SY, Yoo JS, Kim JY, Kim JF, Hur CG
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/21337514/

Education / Career
Article	The genome-scale metabolic network analysis of Zymomonas mobilis ZM4 explains physiological features and suggests ethanol and succinic acid production strategies
Announcements	Microb Cell Fact	Date of publication	2010-11
Co-researcher	Lee KY, Park JM, Kim TY, Yun H, Lee SY
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/21092328/

Education / Career
Article	Prediction of novel synthetic pathways for the production of desired chemicals
Announcements	BMC Syst Biol	Date of publication	2010-03
Co-researcher	Cho A, Yun H, Park JH, Lee SY, Park S
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/20346180/

Education / Career
Article	Microbial small heat shock proteins and their use in biotechnology
Announcements	biotechadv	Date of publication	2008-11
Co-researcher	Han MJ, Yun H, Lee SY
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/18789382/

Education / Career
Article	Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network
Announcements	Appl Microbiol Biotechnol	Date of publication	2008-10
Co-researcher	Lee J, Yun H, Feist AM, Palsson BO, Lee SY
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/18758767/

Education / Career
Article	EcoProDB: The Escherichia coli protein database
Announcements	Bioinformatics	Date of publication	2007-09
Co-researcher	Yun H, Lee JW, Jeong J, Chung J, Park JM, Myoung HN, Lee SY
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/17623702/

Education / Career
Article	MFAML: A standard data structure for representing and exchanging metabolic flux models
Announcements	Bioinformatics	Date of publication	2005-08
Co-researcher	Yun H, Lee DY, Jeong J, Lee S, Lee SY
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/15905275/

Education / Career
Article	MetaFluxNet: The management of metabolic reaction information and quantitative metabolic flux analysis
Announcements	Bioinformatics	Date of publication	2003-11
Co-researcher	Lee DY, Yun H, Park S, Lee SY
Pubmed URL	https://www.ncbi.nlm.nih.gov/pubmed/14594721/

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